ATP2B1 antibody

Catalog No. ABIN7468010

Product Details anti-ATP2B1 Antibody

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PMCA1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ATP2B1

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Alternative Name: ATPase plasma membrane Ca2+ transporting 1 (ATP2B1 Products)

Synonyms: PMCA1 antibody, PMCA1kb antibody, PMCA antibody, 2810442I22Rik antibody, E130111D10Rik antibody, Pmca1 antibody, ATP2B1 antibody, DKFZp459A1127 antibody, atp2b1 antibody, Pmca1a antibody, Pmca1b antibody, Pmca1c antibody, pmca1 antibody, pmca1a antibody, sb:cb801 antibody, si:dkey-18o7.1 antibody, wu:fe47b06 antibody, wu:fi41d01 antibody, atp2b1b antibody, ATPase plasma membrane Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, plasma membrane 1 antibody, plasma membrane calcium-transporting ATPase 2 antibody, ATPase, Ca++ transporting, plasma membrane 1a antibody, ATPase, Ca++ transporting, plasma membrane 1 L homeolog antibody, ATP2B1 antibody, Atp2b1 antibody, atp2b1 antibody, LOC100180580 antibody, atp2b1a antibody, atp2b1.L antibody

Background:

Synonyms: ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Molecular Weight: 139 kDa

Gene ID: 490

UniProt: P20020

Pathways: Ribonucleoside Biosynthetic Process