GRIN1/NMDAR1 antibody (pSer896)

Catalog No. ABIN744293

The Rabbit Polyclonal anti-GRIN1/NMDAR1 antibody has been validated for WB, ELISA, IHC (p), IF (cc), IF (p), ICC and IHC (fro). It is suitable to detect GRIN1/NMDAR1 in samples from Mouse.

Quick Overview for GRIN1/NMDAR1 antibody (pSer896) (ABIN744293)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GRIN1/NMDAR1 Antibody

Binding Specificity: pSer896

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser896

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: NMDAR1

Background:

Synonyms: NMDAR1 C1 (phospho S896), p-NMDAR1 C1 (phospho S896), NMDAR1(Phospho-Ser896), NMDAR1(Phospho-S896), NMDAR1 C1 (phospho S896), p-NMDAR1(S896), p-NMDAR1(Ser896), NMDA-NR1, N-Methyl-d-Asprtate receptor 1, GRIN1, NMDA1, NR1, Glutamate [NMDA] receptor subunit zeta 1, Glutamate receptor ionotropic N methyl D aspartate 1, Grin 1, Grin1, N methyl D aspartate receptor channel, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA NR1, NMDA R1, NMDA receptor 1, NMDA1, NMDAR 1, NMDAR, NR 1, NMDZ1_HUMAN.

Background: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Gene ID: 2902

UniProt: Q05586

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity