IKK alpha antibody

Catalog No. ABIN7880506

The Rabbit Monoclonal anti-IKK alpha antibody (Clone GOD-3) (ABIN7880506) specifically detects IKK alpha in WB. The antibody is reactive with Human samples.

Quick Overview for IKK alpha antibody (ABIN7880506)

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IKK alpha antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GOD-3

Product Details anti-IKK alpha Antibody

Purpose: IKK alpha Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human IKK alpha / CHUK was used as the immunogen for the IKK alpha antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IKK alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the IKK alpha antibody at -20oC.

Target Details for IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Alternative Name: IKK alpha

Background: The CHUK gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [RefSeq]

UniProt: O15111

Pathways: PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins