c-MET antibody

Catalog No. ABIN7881617

The Rabbit Monoclonal anti-c-MET antibody (Clone BFA-13) (ABIN7881617) specifically detects c-MET in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for c-MET antibody (ABIN7881617)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This c-MET antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BFA-13

Product Details anti-c-MET Antibody

Purpose: c-Met Antibody / MET / HGFR

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human c-Met / MET was used as the immunogen for the c-Met antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the c-Met antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the c-Met antibody at -20oC.

Target Details for c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name: c-Met

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. [RefSeq]

UniProt: P08581

Pathways: RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor