PPP3CA antibody (N-Term)

Catalog No. ABIN784223

Product Details anti-PPP3CA Antibody

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects PPP3CA / Calcineurin A (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulfate Precipitation.

Immunogen: kLH conjugated synthetic peptide selected from the N-terminal region of Human PPP3CA. Remarks: Antigen Modification: N-Terminus

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP3CA

Target: PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))

Abstract: PPP3CA Products

Synonyms: CALN antibody, CALNA antibody, CALNA1 antibody, CCN1 antibody, CNA1 antibody, PPP2B antibody, 2900074D19Rik antibody, AI841391 antibody, AW413465 antibody, CN antibody, Caln antibody, Calna antibody, CnA antibody, Calna1 antibody, calcineurin antibody, caln antibody, calna antibody, calna1 antibody, ccn1 antibody, cna1 antibody, ppp2b antibody, fj46e08 antibody, si:dkeyp-79c2.2 antibody, wu:fj46e08 antibody, ppp3ca antibody, protein phosphatase 3 catalytic subunit alpha antibody, protein phosphatase 3, catalytic subunit, alpha isoform antibody, protein phosphatase 3, catalytic subunit, alpha isozyme antibody, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) antibody, protein phosphatase 3, catalytic subunit, alpha isozyme L homeolog antibody, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform antibody, PPP3CA antibody, Ppp3ca antibody, ppp3ca antibody, ppp3ca.L antibody, LOC100205420 antibody

Background: Calcineurin A alpha (PPP3CA), a PP2B type serine/threonine phosphatase, is a catalytic subunit of calcineurin which acts as a calcium-dependent and calmodulin-stimulated modifier of phosphorylation status. PPP3CA has been shown to function in calcium signaling and is believed to function in the calmodulin activation of calcineurin, motor neuron disease and neuronal reorganization after ischemic injury. Based on studies in knockout mice, PPP3CA has been implicated in learning and memmory via hippocampal cytoskeletal changes.Synonyms: CALNA, CAM-PRP catalytic subunit, CNA, Calmodulin-dependent calcineurin A subunit alpha isoform, PP2B catalytic subunit, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, protein phosphatase 2B catalytic subunit alpha

Gene ID: 5530

NCBI Accession: NP_000935

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling