CDC25B antibody (pSer353) (Alexa Fluor 350)
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- Target See all CDC25B Antibodies
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
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Binding Specificity
- pSer353
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDC25B antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB)
- Specificity
- This phosphorylation site is homologous to that of Ser351 in Mouse and Ser 349 in Rat.
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser353
- Isotype
- IgG
- Top Product
- Discover our top product CDC25B Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
- Alternative Name
- Cdc25b (CDC25B Products)
- Synonyms
- CDC25B antibody, AI604853 antibody, cell division cycle 25B antibody, cdc25b antibody, CDC25B antibody, Cdc25b antibody
- Background
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Synonyms: M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2
Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
- Gene ID
- 994
- UniProt
- P30305
- Pathways
- Cell Division Cycle, M Phase, Autophagy
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