Frataxin antibody (Middle Region)
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- Target See all Frataxin (FXN) Antibodies
- Frataxin (FXN)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Frataxin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse (Murine)
- Purification
- Purified
- Immunogen
- Fxn antibody was raised in rabbit using the middle region of Fxn as the immunogen
- Top Product
- Discover our top product FXN Primary Antibody
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- Application Notes
- Optimal conditions should be determined by the investigator.
- Comment
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Fxn Blocking Peptide, catalog no. 33R-9164, is also available for use as a blocking control in assays to test for specificity of this Fxn antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Frataxin (FXN)
- Alternative Name
- Fxn (FXN Products)
- Synonyms
- zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
- Background
- Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1. Synonyms: Polyclonal Fxn antibody, Anti-Fxn antibody, frataxin antibody, FA antibody, FARR antibody, Frda antibody, X25 antibody.
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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