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Frataxin antibody (Middle Region)

FXN Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN928236
  • Target See all Frataxin (FXN) Antibodies
    Frataxin (FXN)
    Binding Specificity
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 64
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 58
    • 13
    Rabbit
    Clonality
    • 60
    • 11
    Polyclonal
    Conjugate
    • 40
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Frataxin antibody is un-conjugated
    Application
    • 54
    • 39
    • 21
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine)
    Purification
    Purified
    Immunogen
    Fxn antibody was raised in rabbit using the middle region of Fxn as the immunogen
    Top Product
    Discover our top product FXN Primary Antibody
  • Application Notes
    Optimal conditions should be determined by the investigator.
    Comment

    Fxn Blocking Peptide, catalog no. 33R-9164, is also available for use as a blocking control in assays to test for specificity of this Fxn antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    Frataxin (FXN)
    Alternative Name
    Fxn (FXN Products)
    Synonyms
    zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
    Background
    Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1. Synonyms: Polyclonal Fxn antibody, Anti-Fxn antibody, frataxin antibody, FA antibody, FARR antibody, Frda antibody, X25 antibody.
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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