SPACA1 antibody (N-Term)

Catalog No. ABIN928305

Product Details anti-SPACA1 Antibody

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPACA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SPACA1 antibody was raised in rabbit using the N terminal of SPACA1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPACA1 Blocking Peptide, catalog no. 33R-9051, is also available for use as a blocking control in assays to test for specificity of this SPACA1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SPACA1

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Alternative Name: SPACA1 (SPACA1 Products)

Synonyms: SAMP32 antibody, 1700124L11Rik antibody, 4930540L03Rik antibody, sperm acrosome associated 1 antibody, SPACA1 antibody, Spaca1 antibody

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. Synonyms: Polyclonal SPACA1 antibody, Anti-SPACA1 antibody, sperm acrosome associated 1 antibody, MGC32952 antibody, SAMP32 antibody.