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Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (C-Term) antibody Primary Antibody

NCF4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN929086
$672.32
Plus shipping costs $45.00
50 μg
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  • Target
    Neutrophil Cytosolic Factor 4, 40kDa (NCF4)
    Binding Specificity
    • 18
    • 15
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 87
    • 30
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    Human
    Host
    • 75
    • 7
    • 6
    Rabbit
    Clonality
    • 85
    • 3
    Polyclonal
    Conjugate
    • 40
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 42
    • 26
    • 26
    • 26
    • 19
    • 12
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    NCF4 antibody was raised in rabbit using the C terminal of NCF4 as the immunogen
  • Application Notes
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    NCF4 Blocking Peptide, catalog no. 33R-7359, is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    Neutrophil Cytosolic Factor 4, 40kDa (NCF4)
    Alternative Name
    NCF4 (NCF4 Antibody Abstract)
    Synonyms
    p40phox, AI451400, NCF, P40PHOX, SH3PXD4, neutrophil cytosolic factor 4, ncf4, Ncf4, NCF4
    Background
    NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. Synonyms: Polyclonal NCF4 antibody, Anti-NCF4 antibody, neutrophil cytosolic factor 4, 40kDa antibody, MGC3810 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody.
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