AXL antibody (C-Term)

Catalog No. ABIN929112

Product Details anti-AXL Antibody

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: AXL antibody was raised in rabbit using the C terminal of AXL as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

AXL Blocking Peptide, catalog no. 33R-7673, is also available for use as a blocking control in assays to test for specificity of this AXL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL (AXL Products)

Synonyms: JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody

Background: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. Synonyms: Polyclonal AXL antibody, Anti-AXL antibody, AXL receptor tyrosine kinase antibody, JTK11 antibody, UFO antibody.

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin