RUNX1 antibody

Catalog No. ABIN930965

Product Details anti-RUNX1 Antibody

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: RUNX1 antibody was raised in mouse using recombinant Human Runt-Related Transcription Factor 1 (Acute Myeloid Leukemia 1, Aml1 Oncogene) (Runx1)

Clone: RUNXA3B6

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: RUNX1 antibody in PBS (3.0 mM KCl,1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 PO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1 (RUNX1 Products)

Synonyms: RUNX1 antibody, runx1 antibody, AI462102 antibody, AML1 antibody, Cbfa2 antibody, Pebp2a2 antibody, Pebpa2b antibody, AML1-EVI-1 antibody, AMLCR1 antibody, CBFA2 antibody, EVI-1 antibody, PEBP2aB antibody, runxa antibody, Runx-1 antibody, XAML antibody, Xaml1 antibody, aml antibody, aml-1 antibody, aml1 antibody, aml1-evi-1 antibody, amlcr1 antibody, cbfa2 antibody, evi-1 antibody, pebp2ab antibody, Aml1 antibody, uncharacterized LOC473981 antibody, runt-related transcription factor antibody, runt related transcription factor 1 antibody, runt-related transcription factor 1 antibody, runt related transcription factor 1 L homeolog antibody, LOC473981 antibody, runt antibody, Runx1 antibody, RUNX1 antibody, runx1 antibody, runx1.L antibody

Background: RUNX1 is a eukaryotic gene and the protein encoded by this gene is a transcription factor associated with M2 AML, a type of leukemia. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-alpha (CBFalpha). RUNX proteins form a heterodimeric complex with CBFbeta which confers increased DNA binding and stability to the complex. Synonyms: Monoclonal RUNX1 antibody, Anti-RUNX1 antibody, Runt-related transcription factor 1 antibody, AML1 antibody, CBFA2 antibody, EVI-1 antibody, AMLCR1 antibody, PEBP2aB antibody, AML1-EVI-1 antibody.