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SORL1 antibody (AA 2159-2214)
SORL1
Reactivity: Human
ELISA, WB
Host: Mouse
Monoclonal
7D7B11
unconjugated
Product Details anti-SORL1 Antibody
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Target
See all SORL1 Antibodies
SORL1
(Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
Binding Specificity
All epitopes for SORL1 antibodies
AA 2159-2214
Reactivity
All reactivities for SORL1 antibodies
Human
Host
All hosts for SORL1 antibodies
Mouse
Clonality
All clonalities for SORL1 antibodies
Monoclonal
Conjugate
All conjugates for SORL1 antibodies
This SORL1 antibody is un-conjugated
Application
All applications for SORL1 antibodies
ELISA, Western Blotting (WB)
Immunogen
SORL1 antibody was raised in Mouse using a purified recombinant fragment of SORL1(aa2159-2214) expressed in E. coli as the immunogen.
Clone
7D7B11
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for SORL1
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Target
SORL1
(Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
Alternative Name
SORL1 (SORL1 Products )
Synonyms
SORL1 antibody, C11orf32 antibody, LR11 antibody, LRP9 antibody, SORLA antibody, SorLA-1 antibody, gp250 antibody, SorLA antibody, 2900010L19Rik antibody, AI596264 antibody, AW261561 antibody, mSorLA antibody, Lr11 antibody, RGD619914 antibody, sortilin related receptor 1 antibody, sortilin-related receptor antibody, sortilin-related receptor, L(DLR class) A repeats containing antibody, sortilin-related receptor, L(DLR class) A repeats-containing antibody, sortilin-related receptor, LDLR class A repeats-containing antibody, sorl1 antibody, LOC582560 antibody, SORL1 antibody, Sorl1 antibody
Background
SORL1 is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. Synonyms: Monoclonal SORL1 antibody, Anti-SORL1 antibody, Sortilin related receptor L A repeats containing antibody.
Pathways
Smooth Muscle Cell Migration
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