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TERT antibody (Internal Region)
TERT
Reactivity: Human
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-TERT Antibody
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Target
See all TERT Antibodies
TERT
(Telomerase Reverse Transcriptase (TERT))
Binding Specificity
All epitopes for TERT antibodies
AA 597-611, Internal Region
Reactivity
All reactivities for TERT antibodies
Human
Host
All hosts for TERT antibodies
Goat
Clonality
All clonalities for TERT antibodies
Polyclonal
Conjugate
All conjugates for TERT antibodies
This TERT antibody is un-conjugated
Application
All applications for TERT antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-QLRELSEAEV RQHRE
Specificity
This antibody recognizes TERT (597-611). It is expected to recognize both reported isoforms (NP_937983.2, (NP_001180305.1).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_937983.2, NP_001180305.1. Genename: TERT
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TERT
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Target
TERT
(Telomerase Reverse Transcriptase (TERT))
Alternative Name
TERT (TERT Products )
Synonyms
CMM9 antibody, DKCA2 antibody, DKCB4 antibody, EST2 antibody, PFBMFT1 antibody, TCS1 antibody, TP2 antibody, TRT antibody, hEST2 antibody, hTRT antibody, chTERT antibody, Tert antibody, ATTERT antibody, F5E19.190 antibody, F5E19_190 antibody, telomerase reverse transcriptase antibody, tert antibody, TR antibody, est2 antibody, tcs1 antibody, telomerase antibody, tert-A antibody, tp2 antibody, trt antibody, xTERT antibody, telomerase reverse transcriptase antibody, Telomerase Reverse Transcriptase antibody, Tertp antibody, Telomerase catalytic subunit antibody, telomerase reverse transcriptase L homeolog antibody, TERT antibody, trt-1 antibody, Tert antibody, tert antibody, CMU_003490 antibody, VDBG_04487 antibody, GL50803_16225 antibody, tert.L antibody
Background
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.Synonyms: EST2, HEST2, TCS1, TRT, Telomerase catalytic subunit, Telomerase reverse transcriptase, Telomerase-associated protein 2
Gene ID
7015
NCBI Accession
NP_001180305
Pathways
Telomere Maintenance
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