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TGFBR2 antibody (N-Term)
TGFBR2
Reactivity: Human, Mouse
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TGFBR2 Antibody
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Target
See all TGFBR2 Antibodies
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Binding Specificity
All epitopes for TGFBR2 antibodies
AA 20-48, N-Term
Reactivity
All reactivities for TGFBR2 antibodies
Human, Mouse
Host
All hosts for TGFBR2 antibodies
Rabbit
Clonality
All clonalities for TGFBR2 antibodies
Polyclonal
Conjugate
All conjugates for TGFBR2 antibodies
This TGFBR2 antibody is un-conjugated
Application
All applications for TGFBR2 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects TGFBR2 (N-term).
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse
Purification
Protein A column followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of human TGFBR2
Isotype
Ig Fraction
Top Product
Discover our top product TGFBR2 Primary Antibody
Alternatives
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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 241-330) antibody
TGFBR2
Reactivity: Human, Mouse, Rat, Rabbit, Cow
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Target Details for TGFBR2
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Target
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Alternative Name
TGFBR2 (TGFBR2 Products )
Synonyms
AAT3 antibody, FAA3 antibody, LDS1B antibody, LDS2B antibody, MFS2 antibody, RIIC antibody, TAAD2 antibody, TGFR-2 antibody, TGFbeta-RII antibody, 1110020H15Rik antibody, AU042018 antibody, DNIIR antibody, RIIDN antibody, TBR-II antibody, TbetaR-II antibody, TbetaRII antibody, TGFBR2 antibody, TBETA-RII antibody, TGFBRII antibody, TGF-beta 2 antibody, Tgfbr2T antibody, cb537 antibody, tgfbr2 antibody, wu:fj05c10 antibody, zgc:110498 antibody, transforming growth factor beta receptor 2 antibody, transforming growth factor, beta receptor II antibody, transforming growth factor, beta receptor 2 antibody, transforming growth factor beta receptor 2b antibody, TGFBR2 antibody, Tgfbr2 antibody, tgfbr2b antibody
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.Synonyms: TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFR-2, TbetaR-II, Transforming growth factor-beta receptor type II
Gene ID
7048
NCBI Accession
NP_001020018
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