Presenilin 1 antibody
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- Target See all Presenilin 1 (PSEN1) Antibodies
- Presenilin 1 (PSEN1)
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Reactivity
- Human, Mouse, Rat, Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Presenilin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- The immunogenic peptide sequences from Presenilin-1, shows 100 % homology to human, xenopus, mouse and rat Presenilin-1. There is no significant homology with other known proteins. The Presenilin-1 antibody cross-reactivity in other species is not known. The appropriate control immunogenic peptides are also available to confirm specificity of antibodies.
- Purification
- Immunoaffinity purified
- Immunogen
- 15 mer peptide locating to the large hydrophilic loop of human or mouse Presenilin-1.
- Isotype
- IgG
- Top Product
- Discover our top product PSEN1 Primary Antibody
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- Application Notes
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Approved: ELISA (1:10000 - 1:100000), WB (1:1000 - 1:5000)
Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry. Western Blot: 1:1000-1:5000 for neat serum and 1-10 μg/mL for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well. Immunoprecipitations: We recommend 5-10 μL neat serum or 1-10 μg affinity pure antibody per 100 μg of tissue. Immunohistochemistry & Immunofluorescence: We recommend the use of affinity purified antibody at 2-20 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
- Sterile PBS. Resuspend to 100 μL
- Concentration
- Lot specific
- Buffer
- PBS, 0.1 % BSA.
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- Presenilin 1 (PSEN1)
- Alternative Name
- PSEN1 / Presenilin 1 (PSEN1 Products)
- Synonyms
- pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
- Background
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Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease
Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1 - Gene ID
- 5663
- UniProt
- P49768
- Pathways
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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