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CD14 antibody

CD14 Reactivity: Human IHC, ELISA Monoclonal unconjugated
Catalog No. ABIN965766
  • Target See all CD14 Antibodies
    CD14
    Reactivity
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    Human
    Host
    Please inquire
    Clonality
    • 204
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    Monoclonal
    Conjugate
    • 112
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    This CD14 antibody is un-conjugated
    Application
    • 187
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    Immunohistochemistry (IHC), ELISA
    Specificity
    Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).
    Purification
    Antibodies are purified by protein G affinity chromatography.
    Isotype
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    IHC: Dilution 1:200-1:400
    ELISA: Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.2%BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
    Gene ID
    929
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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