CD14 antibody
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- Target See all CD14 Antibodies
- CD14
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Reactivity
- Human
- Host
- Please inquire
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Clonality
- Monoclonal
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Conjugate
- This CD14 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Specificity
- Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).
- Purification
- Antibodies are purified by protein G affinity chromatography.
- Isotype
- IgG1
- Top Product
- Discover our top product CD14 Primary Antibody
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- Application Notes
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IHC: Dilution 1:200-1:400
ELISA: Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.2%BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- CD14
- Alternative Name
- CD14 (CD14 Products)
- Synonyms
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- Background
- CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
- Gene ID
- 929
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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