c-MYC antibody

Catalog No. ABIN966619

Product Details anti-c-MYC Antibody

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-MYC antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: Myc (Ab-58) antibody detects endogenous levels of total Myc protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Myc around the phosphorylation site of threonine 58 (L-P-TP-P-P).

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-c-MYC antibody (ABIN966619)

Abé: "Hormonal control of meiosis initiation in the testis from Japanese newt, Cynops pyrrhogaster." in: Zoological science, Vol. 21, Issue 7, pp. 691-704, (2004) (PubMed).

Jin, Gao, Flagg, Deng: "Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 40209-19, (2004) (PubMed).

Baudino, Cleveland: "The Max network gone mad." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 691-702, (2001) (PubMed).

Henriksson, Lüscher: "Proteins of the Myc network: essential regulators of cell growth and differentiation." in: Advances in cancer research, Vol. 68, pp. 109-82, (1996) (PubMed).

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: Myc Proto-Oncogene protein (MYC Products)

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect