anti-Mouse (Murine) Caspase 1 antibody for Immunohistochemistry

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
Epitope
AA 342-391, pSer376
38
15
13
12
11
10
7
6
6
5
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
253
92
72
8
3
2
2
1
1
1
1
1
1
1
Host
Rabbit
236
40
8
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
18
14
7
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
253
136
116
84
31
26
16
7
6
5
3
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN1531644
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.712301 ABIN1532666 IHC ELISA WB Rabbit IgG AA 342-391 Log in to see Polyclonal 3
8.712301 ABIN252521 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468 24
8.712301 ABIN2705671 IHC WB Rabbit Center Log in to see Polyclonal
8.712301 ABIN266745 IHC (fro) IHC (p) IHC WB Rabbit Log in to see Polyclonal
1 ABIN4287999 IHC IHC (p) WB Rabbit cleaved, full length Log in to see Polyclonal 1
1 ABIN3183664 ELISA IHC WB Rabbit IgG Ser197 Log in to see Polyclonal
1 ABIN4288024 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468
1 ABIN3182631 ELISA IHC WB Rabbit IgG pSer376 Log in to see Polyclonal
1 ABIN1585732 ELISA FACS IHC WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4288000 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468
1 ABIN1077907 ICC IHC IP WB Rabbit IgG AA 119-296 Log in to see Polyclonal
1 ABIN3021171 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1732658 IHC (p) IP IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN4903134 IF IHC WB Mouse IgG Log in to see
1 ABIN4288018 IHC IHC (p) WB DyLight 405 Mouse IgG1 kappa Log in to see 14F468
1 ABIN4288022 IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 kappa Log in to see 14F468
1 ABIN4288021 IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 kappa Log in to see 14F468
1 ABIN4288023 IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 kappa Log in to see 14F468
1 ABIN4288020 IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 kappa Log in to see 14F468
1 ABIN4288014 IHC IHC (p) WB PerCP Mouse IgG1 kappa Log in to see 14F468

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope AA 342-391, pSer376
(38), (15), (13), (12), (11), (10), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(253), (92), (72), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(236), (40), (8), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(18), (14), (7), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(253), (136), (116), (84), (31), (26), (16), (7), (6), (5), (3), (3), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) Images
Specificity

Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.

PhosphorylationH:S376 M:S374 R:S374

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.
Isotype IgG

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Antigen
Alternative Name Caspase 1 (CASP1 Antibody Abstract)
Background

Synonyms: CASP-1, caspase-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

NCBI Gene Symbol: CASP1

Molecular Weight 29 kDa
Gene ID 834
OMIM 147678
UniProt P29466
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
Comment

Unigene-Number: Hs.2490 (NCBI Gene Symbol: CASP1)

Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months

References for anti-Caspase 1 antibody (ABIN1531644)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Background publications

Feng, Li, Leung, Auersperg: "Caspase-1zeta, a new splice variant of the caspase-1 gene." in: Genomics, Vol. 84, Issue 3, pp. 587-91, 2004

Agostini, Martinon, Burns, McDermott, Hawkins, Tschopp: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004

Thornberry, Bull, Calaycay, Chapman, Howard, Kostura, Miller, Molineaux, Weidner, Aunins: "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes." in: Nature, Vol. 356, Issue 6372, pp. 768-74, 1992

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (AA 342-391), (pSer376) antibody (ABIN1531644) Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) An...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) (AA 342-391), (pSer376) antibody (ABIN1531644) Immunohistochemistry analysis of paraffin-embedded human brain, using Caspase 1 (Phos...