anti-Human Clusterin antibody for Immunocytochemistry

Recommended Clusterin Antibody (supplied by: Log in to see )

Antigen
Clusterin (CLU) Antibodies
  • LOC100136120
  • clu
  • MGC53055
  • zgc:73352
  • xclu
  • MGC89163
  • CLU
  • APO-J
  • APOJ
  • CLI
  • CLU1
  • CLU2
  • KUB1
  • NA1/NA2
  • SGP-2
  • SGP2
  • SP-40
  • TRPM-2
  • TRPM2
  • DAG
  • RATTRPM2B
  • SP40
  • TRPM2B
  • Trpm2
  • Trpmb
  • AI893575
  • ApoJ
  • Cli
  • D14Ucla3
  • Sgp-2
  • Sgp2
  • Sugp-2
  • GP80
  • gpIII
  • 40
  • clusterin-1
  • clusterin L homeolog
  • clusterin
  • Clusterin
  • LOC100136120
  • clu.L
  • clu
  • CLU
  • clus
  • Clu
  • LOC101113728
Reactivity
Human
294
70
65
20
19
7
3
3
2
2
1
1
Host
Mouse
190
117
81
10
5
2
Clonality
Monoclonal
Conjugate
This Clusterin antibody is un-conjugated
38
31
11
9
8
7
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
355
233
173
80
58
57
34
33
30
29
11
7
2
1
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Catalog No. ABIN94264
$ 394.53
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13 ABIN6260901 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
10 ABIN1077937 ICC IHC WB Rabbit IgG AA 228-449 Log in to see Polyclonal 0
7 ABIN239817 ELISA ICC IHC IHC (p) WB Mouse IgG1 Log in to see Hs-3 0
7 ABIN3201572 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 228-449 Log in to see 0
4 ABIN2469990 ICC IHC ELISA Mouse IgG1 Log in to see Hs-3 0
4 ABIN1723370 ICC IHC (p) ELISA Mouse IgG1 Log in to see Hs-3 0
4 ABIN5575628 ELISA ICC IHC (p) Mouse IgG1 Log in to see Hs-3 0
1 ABIN1839608 ICC ELISA WB Mouse IgG1 Log in to see Hs-3 0
1 ABIN2595546 ICC IF IHC ELISA WB Mouse IgG1 Log in to see s-3 0
1 ABIN594376 ICC ELISA WB Mouse IgG1 Log in to see HS-3 0
1 ABIN323977 ICC IF IHC ELISA WB Mouse IgG1 Log in to see 0
1 ABIN108488 ICC IF IHC ELISA WB Mouse Log in to see Hs-3 4
1 ABIN2769525 ELISA ICC IHC (p) Mouse IgG1 Log in to see Hs-3 0
1 ABIN296850 ICC IP IHC WB Mouse IgG1 Log in to see CLI-9 0
1 ABIN3200114 ELISA ICC IHC (p) WB Mouse IgG1 Log in to see Hs-3 0
1 ABIN5688470 ICC IHC IP WB Mouse IgG1 Log in to see CLI-9 0
1 ABIN5568683 FACS ICC IF IHC FITC Rabbit AA 23-449 Log in to see Polyclonal 0
1 ABIN5568685 FACS ICC IF IHC PE Rabbit AA 23-449 Log in to see Polyclonal 0
1 ABIN5568681 FACS ICC IF IHC APC Rabbit AA 23-449 Log in to see Polyclonal 0
1 ABIN199830 ICC IHC IHC (fro) IP WB Mouse IgG1 Log in to see CLI-9 0

General

Antigen Clusterin (CLU) Antibodies
Reactivity Human
(294), (70), (65), (20), (19), (7), (3), (3), (2), (2), (1), (1)
Host Mouse
(190), (117), (81), (10), (5), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Clusterin antibody is un-conjugated
(38), (31), (11), (9), (8), (7), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(355), (233), (173), (80), (58), (57), (34), (33), (30), (29), (11), (7), (2), (1)
Pubmed 6 references available
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Product Details anti-Clusterin Antibody

Target Details Clusterin Application Details Handling References for anti-Clusterin antibody (ABIN94264) Images
No Cross-Reactivity Pig (Porcine), Cow (Bovine), Dog (Canine), Cat (Feline)
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Immunogen Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
Clone Hs-3
Isotype IgG1
Plasmids, Primers & others

Target Details Clusterin

Product Details anti-Clusterin Antibody Application Details Handling References for anti-Clusterin antibody (ABIN94264) Images back to top
Antigen
Alternative Name CLU (CLU Antibody Abstract)
Background Clusterin (APO J, SGP-2, TRPM-2, SP-40, pADHC-9, CLJ, T64, GP III, XIP8) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30 % of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. It is a conserved secreted glycoprotein expressed by a wide range of tissues and being implicated in many physiological processes, including e.g. lipid transportation, complement inhibition, tissue remodeling, membrane recycling, or clearence of cellular debris. It is nearly ubiqitously expressed in most mammalian tissues and can be found in plasma, milk, urine, cerebrospinal fluid and semen. Clusterin is able to bind and form complexes with numerous partners (immunoglobulins, lipids, heparin, bacteria, complement components, paraoxonase, beta amyloid, leptin etc.) and is expressed in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. A genuine function of clusterin is still enigmatic.
Pathways Apoptosis, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-Clusterin Antibody Target Details Clusterin Handling References for anti-Clusterin antibody (ABIN94264) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details References for anti-Clusterin antibody (ABIN94264) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-Clusterin antibody (ABIN94264)

Product Details anti-Clusterin Antibody Target Details Clusterin Application Details Handling Images back to top
Background publications

Pérez-Rubio, Eiros Bouza, Castrodeza Sanz: "[Evaluation of the influenza a H1N1 vaccination in Castilla and Leon regions, Spain]." in: Medicina clínica, Vol. 135, Issue 12, pp. 543-5, 2010

Schepeler, Mansilla, Christensen, Orntoft, Andersen: "Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling." in: Journal of molecular signaling, Vol. 2, pp. 6, 2007

Cochrane, Wang, Muramaki, Gleave, Nelson: "Differential regulation of clusterin and its isoforms by androgens in prostate cells." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2278-87, 2007

Shannan, Seifert, Boothman, Tilgen, Reichrath: "Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control." in: Journal of molecular histology, Vol. 37, Issue 5-7, pp. 183-8, 2006

Pajak, Orzechowski: "Clusterin: the missing link in the calcium-dependent resistance of cancer cells to apoptogenic stimuli." in: Postȩpy higieny i medycyny doświadczalnej (Online), Vol. 60, pp. 45-51, 2006

Product cited in:

Capková, Geussová, Peknicová: "New monoclonal antibody to human apolipoprotein J." in: Folia biologica, Vol. 48, Issue 1, pp. 40-2, 2002