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CDC25C Products

(Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

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This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008].

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Featured CDC25C Categories

CDC25C Antibodies

High quality antibodies with extensive validation data.

CDC25C ELISA Kits

Reliable ELISA kits for a wide range of species.

CDC25C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDC25C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP, RNAi
Validations
  • (7)
Cat. No. ABIN560272
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, IP
Validations
  • (4)
Cat. No. ABIN7127412
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6260678
Quantity 100 μL
Datasheet Datasheet

Recommended CDC25C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380294
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5691926
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended CDC25C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348798
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348800
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3134226
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CDC25C products

Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." in: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

Peng, Qi, Miao, Ren: "1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase." in: Acta pharmacologica Sinica, Vol. 38, Issue 4, pp. 561-570, (2017) (PubMed).

Yin, Jiang, Peng, Cui, Zhou, He, Zuo, Ouyang, Fan, Fang: "The molecular mechanism of G2M cell cycle arrest induced by AFB1 in the jejunum." in: Oncotarget, Vol. 7, Issue 24, pp. 35592-35606, (2016) (PubMed).

Ghate, Das, Chaudhuri, Panja, Mandal: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." in: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).

Guo, Cui, Peng, Fang, Zuo, Deng, Wang, Wu, Chen, Deng: "Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney." in: Oncotarget, Vol. 6, Issue 34, pp. 35964-77, (2015) (PubMed).

Ling, Lu, He, Xiao, Jiang, Su: "Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line." in: Oncology reports, Vol. 32, Issue 5, pp. 2274-82, (2014) (PubMed).

Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: "An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7." in: PLoS ONE, Vol. 8, Issue 12, pp. e82293, (2013) (PubMed).

Zheng, Kosti, Loffredo, Bowman, Mechanic, Perlmutter, Jones, Shields, Harris: "Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, (2010) (PubMed).

Busch, Barton, Morgenstern, Götz, Günther, Noll, Montenarh: "The G2/M checkpoint phosphatase cdc25C is located within centrosomes." in: The international journal of biochemistry & cell biology, Vol. 39, Issue 9, pp. 1707-13, (2007) (PubMed).

Chen, Zhang, Bower, Lu, Leonard, Ding, Castranova, Piwnica-Worms, Shi: "Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 4, pp. 1990-5, (2002) (PubMed).

Synonyms and alternative names related to CDC25C

cell division cycle 25C (CDC25C), cell division cycle 25C (cdc25c), cell division cycle 25C (Cdc25c), cell division cycle 25C S homeolog (cdc25c.S), cdc25, CDC25, Cdc25, cdc25-3, CDC25C, PPP1R60, xcdc25-3, xcdc25c

Protein level used designations for CDC25C

  • cell division cycle 25 homolog C (S. pombe)
  • m-phase inducer phosphatase 3-like
  • cell division cycle 25 homolog C
  • cell division cycle 25C
  • Dual specificity phosphatase Cdc25C
  • M-phase inducer phosphatase 3
  • dual specificity phosphatase Cdc25C
  • dual specificity phosphatase CDC25C
  • mitosis inducer CDC25
  • phosphotyrosine phosphatase
  • protein phosphatase 1, regulatory subunit 60
  • cell cycle phosphatase CDC25C
  • cell division cycle control protein 25C
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