anti-Human COPS8 antibody for Enzyme Immunoassay

Recommended COPS8 Antibody (supplied by: Log in to see )

Antigen
COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) Antibodies
  • CG13383
  • CG33297
  • CG42522
  • CH8
  • Csn8
  • Dch8
  • Dmel\\CG42522
  • Dmel_CG13383
  • csn8
  • l(2)SH1829
  • l(2)SH2 1829
  • cops8
  • MGC76051
  • MGC80215
  • DDBDRAFT_0167123
  • DDBDRAFT_0233107
  • DDB_0167123
  • DDB_0233107
  • MGC86182
  • 9430009J09Rik
  • AA408242
  • Sgn8
  • CSN8
  • zgc:56319
  • zgc:86840
  • CONSTITUTIVE PHOTOMORPHOGENIC 9
  • COP9 SIGNALOSOME SUBUNIT 8
  • DL3095C
  • EMB143
  • EMBRYO DEFECTIVE 143
  • FCAALL.131
  • FUS7
  • FUSCA 7
  • FUSCA PROTEIN FUS7
  • COP9
  • SGN8
  • COP9 signalosome subunit 8
  • COP9 signalosome subunit 8 S homeolog
  • COP9 signalosome complex subunit 8
  • COP9 signalosome subunit 8 L homeolog
  • COP9 signalosome, subunit CSN8
  • CSN8
  • cops8
  • COPS8
  • cops8.S
  • csn8
  • cops8.L
  • Cops8
  • COP9
Epitope
N-Term, AA 1-30
17
13
10
4
4
4
4
1
Reactivity
Human
75
34
33
3
3
3
3
2
1
1
1
Host
Rabbit
67
8
Clonality
Polyclonal
Conjugate
This COPS8 antibody is un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
55
32
13
10
8
6
1
1
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Catalog No. ABIN951663
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554707 EIA WB Rabbit IgG C-Term Log in to see Polyclonal 0

General

Antigen COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) Antibodies
Epitope N-Term, AA 1-30
(17), (13), (10), (4), (4), (4), (4), (1)
Reactivity Human
(75), (34), (33), (3), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(67), (8)
Clonality
Polyclonal
Conjugate This COPS8 antibody is un-conjugated
(4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(55), (32), (13), (10), (8), (6), (1), (1)
Pubmed 3 references available
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Product Details anti-COPS8 Antibody

Target Details COPS8 Application Details Handling References for anti-COPS8 antibody (ABIN951663) Images
Specificity This antibody reacts to COPS8.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS8
Isotype Ig Fraction
Plasmids, Primers & others

Target Details COPS8

Product Details anti-COPS8 Antibody Application Details Handling References for anti-COPS8 antibody (ABIN951663) Images back to top
Antigen
Alternative Name COPS8 (COPS8 Antibody Abstract)
Background The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Synonyms: COP9 signalosome complex subunit 8, CSN8, JAB1-containing signalosome subunit 8, SGN8, Signalosome subunit 8
Molecular Weight 23226 Da
Gene ID 10920
NCBI Accession NP_006701
Pathways Cell Division Cycle

Application Details

Product Details anti-COPS8 Antibody Target Details COPS8 Handling References for anti-COPS8 antibody (ABIN951663) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-COPS8 Antibody Target Details COPS8 Application Details References for anti-COPS8 antibody (ABIN951663) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-COPS8 antibody (ABIN951663)

Product Details anti-COPS8 Antibody Target Details COPS8 Application Details Handling Images back to top
Background publications

Enchev, Schreiber, Beuron, Morris: "Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3." in: Structure (London, England : 1993), Vol. 18, Issue 4, pp. 518-27, 2010

Miyauchi, Kato, Tokunaga, Iwai: "The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16622-31, 2008

Schweitzer, Bozko, Dubiel, Naumann: "CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha." in: The EMBO journal, Vol. 26, Issue 6, pp. 1532-41, 2007

Images

Product Details anti-COPS8 Antibody Target Details COPS8 Application Details Handling References for anti-COPS8 antibody (ABIN951663) back to top
Supplier Images
Western Blotting (WB) image for anti-COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) (AA 1-30), (N-Term) antibody (ABIN951663) COPS8 Antibody (N-term) western blot analysis in Ramos cell line lysates (35µg/...