anti-Human BCL6 antibody for Immunohistochemistry (Formalin-fixed Sections)

Recommended BCL6 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 6 (BCL6) Antibodies
  • bcl5
  • laz3
  • bcl6a
  • znf51
  • zbtb27
  • MGC132260
  • Bcl5
  • BCL5
  • BCL6A
  • LAZ3
  • ZBTB27
  • ZNF51
  • B-cell CLL/lymphoma 6 L homeolog
  • B-cell CLL/lymphoma 6
  • B cell leukemia/lymphoma 6
  • bcl6.L
  • bcl6
  • BCL6
  • Bcl6
Reactivity
Human, Mouse (Murine)
327
123
62
9
6
3
2
1
1
1
1
Host
Mouse
192
130
5
1
Clonality
Monoclonal
Conjugate
This BCL6 antibody is conjugated to APC
13
12
12
9
9
7
5
4
4
4
4
4
4
4
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
181
140
140
100
85
51
25
22
20
13
2
2
2
1
1
1
Supplier
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Catalog No. ABIN6175692
$ 392.62
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN6175699 FACS IF IHC (f) PerCP Mouse IgG1, kappa Log in to see BCL6-850 0
7 ABIN6175700 FACS IF IHC (f) PE Mouse IgG1, kappa Log in to see BCL6-850 0
7 ABIN6175703 FACS IF IHC (f) Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175666 FACS IF IHC (f) CF®405S Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175688 FACS IF IHC (f) CF®488A Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175672 FACS IF IHC (f) CF®543 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175690 FACS IF IHC (f) CF®594 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175674 FACS IF IHC (f) CF®647 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175680 FACS IF IHC (f) CF®568 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175682 FACS IF IHC (f) CF®770 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175668 FACS IF IHC (f) CF405M Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175670 FACS IF IHC (f) CF®640R Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175676 FACS IF IHC (f) CF®555 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175678 FACS IF IHC (f) CF®660R Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175684 FACS IF IHC (f) CF®680 Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175686 FACS IF IHC (f) CF®680R Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175701 FACS IF IHC (f) Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175693 FACS IF IHC (f) Alkaline Phosphatase (AP) Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175695 FACS IF IHC (f) Biotin Mouse IgG1, kappa Log in to see BCL6-850 0
1 ABIN6175697 FACS IF IHC (f) HRP Mouse IgG1, kappa Log in to see BCL6-850 0

General

Antigen B-Cell CLL/lymphoma 6 (BCL6) Antibodies
Reactivity Human, Mouse (Murine)
(327), (123), (62), (9), (6), (3), (2), (1), (1), (1), (1)
Host Mouse
(192), (130), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL6 antibody is conjugated to APC
(13), (12), (12), (9), (9), (7), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
(181), (140), (140), (100), (85), (51), (25), (22), (20), (13), (2), (2), (2), (1), (1), (1)
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Product Details anti-BCL6 Antibody

Target Details BCL6 Application Details Handling Images
Purpose Mouse Monoclonal anti-bcl-6 (BCL6/850), APC Conjugate
Characteristics This antibody recognizes a protein of 95 kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Immunogen Recombinant human bcl-6 protein
Clone BCL6-850
Isotype IgG1, kappa
Plasmids, Primers & others

Target Details BCL6

Product Details anti-BCL6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name bcl-6 (BCL6 Antibody Abstract)
Molecular Weight 95 kDa
Gene ID 604, 478588
UniProt P41182
Pathways Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus

Application Details

Product Details anti-BCL6 Antibody Target Details BCL6 Handling Images back to top
Application Notes Immunohistology formalin-fixed 0.5-1 μg/mL
  • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
  • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
  • Immunofluorescence 1-2 μg/mL
  • Optimal dilution for a specific application should be determined by user
Restrictions For Research Use only

Handling

Product Details anti-BCL6 Antibody Target Details BCL6 Application Details Images back to top
Format Liquid
Concentration 100 μg/mL
Buffer PBS/0.1 % BSA/0.05 % azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Images

Product Details anti-BCL6 Antibody Target Details BCL6 Application Details Handling back to top
Supplier Images
 image for anti-B-Cell CLL/lymphoma 6 (BCL6) antibody (APC) (ABIN6175692) anti-B-Cell CLL/lymphoma 6 (BCL6) antibody (APC)
 image for anti-B-Cell CLL/lymphoma 6 (BCL6) antibody (APC) (ABIN6175692) anti-B-Cell CLL/lymphoma 6 (BCL6) antibody (APC) (Image 2)