anti-Human CD55 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD55 Antibody (supplied by: Log in to see )

Antigen
Complement Decay-Accelerating Factor (CD55) Antibodies
  • CR
  • CROM
  • DAF
  • TC
  • Daf
  • Daf-GPI
  • Daf1
  • GPI-DAF
  • CD55 molecule (Cromer blood group)
  • CD55 molecule, decay accelerating factor for complement
  • CD55
  • Cd55
Reactivity
Human, Non-Human Primate
463
56
24
11
9
3
3
2
2
2
Host
Mouse
368
120
15
10
8
3
3
Clonality
Monoclonal
Conjugate
This CD55 antibody is un-conjugated
58
50
32
19
9
9
8
8
8
7
5
5
5
5
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
375
205
124
106
74
73
43
42
16
13
6
6
6
5
3
2
1
1
1
1
1
1
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Catalog No. ABIN94183
$ 343.07
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.311333 ABIN94184 FACS IHC (p) IP Biotin Mouse IgM Log in to see MEM-118 6
20.311333 ABIN1027693 FACS IHC (p) IP PE Mouse IgM Log in to see MEM-118 6
20.311333 ABIN94185 FACS IHC (p) IP FITC Mouse IgM Log in to see MEM-118 6
11.7556715 ABIN291344 FACS IHC IHC (p) IP Mouse IgM Log in to see MEM-118 0
11.7556715 ABIN731228 IF (p) IHC (p) WB Rabbit IgG AA 300-350 Log in to see Polyclonal 0
10 ABIN5574656 IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
9.997421 ABIN4294818 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
8.7556715 ABIN2618672 ICC IHC IHC (p) WB Rabbit IgG AA 71-330 Log in to see Polyclonal 0
8.497421 ABIN4294817 IHC IHC (p) Rabbit IgG Log in to see Polyclonal 1
7 ABIN3043393 IHC (p) WB Rabbit IgG AA 35-347 Log in to see Polyclonal 0
7 ABIN573971 FACS IHC IHC (p) Mouse IgG1, kappa Log in to see 143-30 0
4 ABIN1995663 ELISA IHC (p) IP WB Rabbit IgG AA 1-353 Log in to see Polyclonal 0
4 ABIN400664 EIA FACS IHC (p) WB Mouse IgM Log in to see MEM-118 0
4 ABIN1724170 FACS IHC (p) IP Mouse IgM Log in to see MEM-118 0
4 ABIN1724079 FACS IHC (p) Mouse IgG1 kappa Log in to see 143-30 0
4 ABIN658718 FACS IF IHC (p) WB Rabbit Ig Fraction AA 51-79, N-Term Log in to see Polyclonal 0
4 ABIN5649861 IHC (p) Rabbit IgG Log in to see Polyclonal 0
2.2417498 ABIN269027 FACS IHC (p) IP IHC Mouse IgM Log in to see MEM-118 0
1 ABIN600851 FACS IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see 67 0
1 ABIN5689937 ELISA IF IHC (p) WB Rabbit IgG AA 360-410 Log in to see Polyclonal 0

General

Antigen Complement Decay-Accelerating Factor (CD55) Antibodies
Reactivity Human, Non-Human Primate
(463), (56), (24), (11), (9), (3), (3), (2), (2), (2)
Host Mouse
(368), (120), (15), (10), (8), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD55 antibody is un-conjugated
(58), (50), (32), (19), (9), (9), (8), (8), (8), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(375), (205), (124), (106), (74), (73), (43), (42), (16), (13), (6), (6), (6), (5), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-CD55 Antibody

Target Details CD55 Application Details Handling References for anti-CD55 antibody (ABIN94183) Images
Specificity The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
HLDA V, WS Code AS S016
Cross-Reactivity (Details) Human, Non-Human Primates
Purification Purified by precipitation and chromatography
Purity > 95 % (by SDS-PAGE)
Immunogen HPB-ALL human T cell line
Clone MEM-118
Isotype IgM
Plasmids, Primers & others

Target Details CD55

Product Details anti-CD55 Antibody Application Details Handling References for anti-CD55 antibody (ABIN94183) Images back to top
Antigen
Alternative Name CD55 (CD55 Antibody Abstract)
Background CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Pathways Complement System, Regulation of Leukocyte Mediated Immunity

Application Details

Product Details anti-CD55 Antibody Target Details CD55 Handling References for anti-CD55 antibody (ABIN94183) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD55 Antibody Target Details CD55 Application Details References for anti-CD55 antibody (ABIN94183) Images back to top
Concentration 1 mg/mL
Buffer Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CD55 antibody (ABIN94183)

Product Details anti-CD55 Antibody Target Details CD55 Application Details Handling Images back to top
Background publications

VanLandingham, Cekic, Cutler, Hoffman, Stein: "Neurosteroids reduce inflammation after TBI through CD55 induction." in: Neuroscience letters, Vol. 425, Issue 2, pp. 94-8, 2007

Abbott, Spendlove, Roversi, Fitzgibbon, Knott, Teriete, McDonnell, Handford, Lea: "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 22023-32, 2007

Miwa, Maldonado, Zhou, Yamada, Gilkeson, Eisenberg, Song: "Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms." in: The American journal of pathology, Vol. 170, Issue 4, pp. 1258-66, 2007

Mikesch, Buerger, Simon, Brandt: "Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies." in: Biochimica et biophysica acta, Vol. 1766, Issue 1, pp. 42-52, 2006

Miwa, Maldonado, Zhou, Sun, Luo, Cai, Werth, Madaio, Eisenberg, Song: "Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice." in: The American journal of pathology, Vol. 161, Issue 3, pp. 1077-86, 2002

Product cited in:

Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, 1999

Images

Product Details anti-CD55 Antibody Target Details CD55 Application Details Handling References for anti-CD55 antibody (ABIN94183) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Complement Decay-Accelerating Factor (CD55) antibody (ABIN94183) Surface staining of human peripheral blood leukocytes by mouse monoclonal anti-CD55 a...
Flow Cytometry (FACS) image for anti-Complement Decay-Accelerating Factor (CD55) antibody (ABIN94183) Surface staining of human peripheral blood cells with anti-CD55 (MEM-118) purified, G...