anti-Non-Human Primate CD55 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD55 Antibody (supplied by: Log in to see )

Antigen
Complement Decay-Accelerating Factor (CD55) Antibodies
  • CR
  • CROM
  • DAF
  • TC
  • Daf
  • Daf-GPI
  • Daf1
  • GPI-DAF
  • CD55 molecule (Cromer blood group)
  • CD55 molecule, decay accelerating factor for complement
  • CD55
  • Cd55
Epitope
Domain SCR4
17
12
9
9
8
8
8
7
7
7
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Non-Human Primate
496
62
24
10
9
3
3
2
2
2
Host
Mouse
401
118
22
10
8
3
3
Clonality
Monoclonal
Conjugate
This CD55 antibody is conjugated to PE
59
50
34
20
13
11
11
11
10
10
6
6
6
6
6
5
5
5
5
5
5
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
414
208
121
107
75
75
43
38
17
9
6
6
6
5
3
2
1
1
1
1
1
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Catalog No. ABIN1027693
$ 366.85
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN94185 FACS IHC (p) IP FITC Mouse IgM Domain SCR4 Log in to see MEM-118 6
1 ABIN94184 FACS IHC (p) IP Biotin Mouse IgM Domain SCR4 Log in to see MEM-118 6
1 ABIN94183 FACS IHC (p) IP Mouse IgM Domain SCR4 Log in to see MEM-118 6

General

Antigen Complement Decay-Accelerating Factor (CD55) Antibodies
Epitope Domain SCR4
(17), (12), (9), (9), (8), (8), (8), (7), (7), (7), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Non-Human Primate
(496), (62), (24), (10), (9), (3), (3), (2), (2), (2)
Host Mouse
(401), (118), (22), (10), (8), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD55 antibody is conjugated to PE
(59), (50), (34), (20), (13), (11), (11), (11), (10), (10), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(414), (208), (121), (107), (75), (75), (43), (38), (17), (9), (6), (6), (6), (5), (3), (2), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-CD55 Antibody

Target Details CD55 Application Details Handling References for anti-CD55 antibody (ABIN1027693) Images
Specificity The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
HLDA V, WS Code AS S016
Characteristics The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Immunogen HPB-ALL human T cell line
Clone MEM-118
Isotype IgM
Plasmids, Primers & others

Target Details CD55

Product Details anti-CD55 Antibody Application Details Handling References for anti-CD55 antibody (ABIN1027693) Images back to top
Antigen
Alternative Name CD55 (CD55 Antibody Abstract)
Background CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Pathways Complement System, Regulation of Leukocyte Mediated Immunity

Application Details

Product Details anti-CD55 Antibody Target Details CD55 Handling References for anti-CD55 antibody (ABIN1027693) Images back to top
Application Notes The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
Restrictions For Research Use only

Handling

Product Details anti-CD55 Antibody Target Details CD55 Application Details References for anti-CD55 antibody (ABIN1027693) Images back to top
Reconstitution No reconstitution is necessary.
Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Avoid prolonged exposure to light.
Storage 4 °C
Storage Comment Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

References for anti-CD55 antibody (ABIN1027693)

Product Details anti-CD55 Antibody Target Details CD55 Application Details Handling Images back to top
Background publications

VanLandingham, Cekic, Cutler, Hoffman, Stein: "Neurosteroids reduce inflammation after TBI through CD55 induction." in: Neuroscience letters, Vol. 425, Issue 2, pp. 94-8, 2007

Abbott, Spendlove, Roversi, Fitzgibbon, Knott, Teriete, McDonnell, Handford, Lea: "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 22023-32, 2007

Miwa, Maldonado, Zhou, Yamada, Gilkeson, Eisenberg, Song: "Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms." in: The American journal of pathology, Vol. 170, Issue 4, pp. 1258-66, 2007

Mikesch, Buerger, Simon, Brandt: "Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies." in: Biochimica et biophysica acta, Vol. 1766, Issue 1, pp. 42-52, 2006

Miwa, Maldonado, Zhou, Sun, Luo, Cai, Werth, Madaio, Eisenberg, Song: "Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice." in: The American journal of pathology, Vol. 161, Issue 3, pp. 1077-86, 2002

Product cited in:

Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, 1999

Images

Product Details anti-CD55 Antibody Target Details CD55 Application Details Handling References for anti-CD55 antibody (ABIN1027693) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Complement Decay-Accelerating Factor (CD55) (Domain SCR4) antibody (PE) (ABIN1027693) Surface staining of human peripheral blood leukocytes by mouse monoclonal anti-CD55 a...