CRBN Antibodies

Donovan, An, Nowak, Yuan, Fink, Berry, Ebert, Fischer: "Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome." in: eLife, Vol. 7, (2019) (PubMed).

Girardini, Maniaci, Hughes, Testa, Ciulli: "Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs." in: Bioorganic & medicinal chemistry, Vol. 27, Issue 12, pp. 2466-2479, (2019) (PubMed).

de Wispelaere, Du, Donovan, Zhang, Eleuteri, Yuan, Kalabathula, Nowak, Fischer, Gray, Yang: "Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations." in: Nature communications, Vol. 10, Issue 1, pp. 3468, (2019) (PubMed).

Zoppi, Hughes, Maniaci, Testa, Gmaschitz, Wieshofer, Koegl, Riching, Daniels, Spallarossa, Ciulli et al.: "Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of ..." in: Journal of medicinal chemistry, (2018) (PubMed).

Olson, Jiang, Erb, Liang, Doctor, Zhang, Zhang, Kwiatkowski, Boukhali, Green, Haas, Nomanbhoy, Fischer, Young, Bradner, Winter, Gray: "Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation." in: Nature chemical biology, Vol. 14, Issue 2, pp. 163-170, (2018) (PubMed).

Peng, Li, Clarkson, Pehar, Lao, Hillmer, Barnhart, Christian, Mitchell, Bendlin, Sandor, Puglielli: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).

Liu, Ye, Zou, Xu, Feng, Zou, Chen, Li, Cang: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, (2014) (PubMed).

Gandhi, Mendy, Waldman, Chen, Rychak, Miller, Gaidarova, Ren, Wang, Breider, Carmel, Mahmoudi, Jackson, Abbasian, Cathers, Schafer, Daniel, Lopez-Girona, Thakurta, Chopra: "Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity." in: British journal of haematology, Vol. 164, Issue 2, pp. 233-44, (2014) (PubMed).

Charoenfuprasert, Yang, Lee, Chao, Chu, Lai, Hsu, Chang, Chen, Chen, Chang, Leu, Shih: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, (2011) (PubMed).

An, Ponthier, Sack, Seebacher, Stadler, Donovan, Fischer: "pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBNubiquitin ligase." in: Nature communications, Vol. 8, pp. 15398 (PubMed).