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This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
LIM homeobox transcription factor 1, beta
, LIM homeo box transcription factor 1B
, LIM homeobox transcription factor 1-beta
, LIM/homeobox protein 1.2
, LIM/homeobox protein LMX1B
, LIM homeobox protein
, LIM/homeobox protein 1
, LIM/homeobox protein LMX-1.2
, homeobox protein LMX-1
, homeodomain protein (lmx)
, LIM homeobox transcription factor 1, beta 1
, LIM homeobox protein 1b
, LIM homeobox transcription factor 1-beta.1