Browse our anti-GRB7 (GRB7) Antibodies

Full name:: anti-Growth Factor Receptor-Bound Protein 7 Antibodies (GRB7)

On www.antibodies-online.com are 101 Growth Factor Receptor-Bound Protein 7 (GRB7) Antibodies from 21 different suppliers available. Additionally we are shipping GRB7 Kits (20) and GRB7 Proteins (11) and many more products for this protein. A total of 141 GRB7 products are currently listed.

Synonyms:: GRB7, mKIAA4028

list all antibodies	Gene Name	GeneID	UniProt
	GRB7	14786	Q03160
	GRB7	84427	Q9QZC5
	GRB7	2886	Q14451
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Most Popular Reactivities for anti-GRB7 (GRB7) Antibodies

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anti-Mouse (Murine) GRB7 Antibodies:

anti-Rat (Rattus) GRB7 Antibodies:

anti-Human GRB7 Antibodies:

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Relevant Pathways for anti-GRB7 Antibodies

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Top referenced anti-GRB7 Antibodies

Human Polyclonal GRB7 Primary Antibody for ELISA, WB - ABIN249513 : Margolis, Silvennoinen, Comoglio, Roonprapunt, Skolnik, Ullrich, Schlessinger: High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

More Antibodies against GRB7 Interaction Partners

Mouse (Murine) Growth Factor Receptor-Bound Protein 7 (GRB7) interaction partners

GRB7 gene expression in uterus during embryo implantation is regulated by Mmu-miR (show MLXIP Antibodies)-193.
Findings illustrate an underlying mechanism by which Grb7 promotes tumorigenesis through the formation of a novel EGFR (show EGFR Antibodies)-Grb7-Ras signaling complex, thereby highlighting the potential strategy of targeting Grb7 as an anti-breast cancer therapy.
The adaptor Grb7 links netrin-1 (show NTN1 Antibodies) signaling to regulation of mRNA translation of kappa opioid receptor (show OPRK1 Antibodies).
Grb7 is identified as an integral component of stress granules.

Human Growth Factor Receptor-Bound Protein 7 (GRB7) interaction partners

Grb7 protein Ras-associating domain oligomerization has been reported.
Study provided a direct link between the signal adapter protein (show TOLLIP Antibodies) Grb7, anti-apoptotic protein Hax1 (show HAX1 Antibodies) isoform 1, and Caspase3-mediated apoptosis pathways, and suggests that besides modulating cell migration and signal transduction, Grb7 may also participate in Hax1 (show HAX1 Antibodies)-related apoptosis pathways mediated by Caspase3.
Suggest close relationship between Grb7 gene amplification and GRB7 protein overexpression in human ovarian cancer. Immunohistochemistry might have limited diagnostic value in these tumors compared to fluorescence in situ hybridization.
Grb7 was found to be significantly related to the biological classification of breast cancer
apo (show C9orf3 Antibodies) Grb7 SH2 domain crystallized in the trigonal space group P63 (show RPE65 Antibodies), whereas the G7-B1-Grb7 SH2 domain complex crystallized in the monoclinic space group P21 (show CDKN1A Antibodies)
The data reveal that Grb7 plays an important role in breast cancer progression, beyond the context of HER2 (show ERBB2 Antibodies)+ve cell types
Grb7 protein interacts with Filamin-a, an actin-crosslinking component of the cell cytoskeleton.
Data suggest that calmodulin controls Grb7-mediated cell migration.
Data propose the phosphorylation state of Grb7-SH2 domain tyrosine residues could control Grb7 dimerization, and dimerization may be an important regulatory step in Grb7 binding to RTKs such as erbB2 (show ERBB2 Antibodies).
GRB7 is a context-dependent oncogene (show RAB1A Antibodies), which modulates the ERBB2 (show ERBB2 Antibodies) signaling pathway through enhanced phosphorylation of ERBB2 (show ERBB2 Antibodies) and Akt (show AKT1 Antibodies).

GRB7 Antigen Profile

Antigen Summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with GRB7

growth factor receptor bound protein 7 (GRB7) antibody
growth factor receptor bound protein 7 (Grb7) antibody

GRB7 antibody
mKIAA4028 antibody

Protein level used designations for GRB7

growth factor receptor-bound protein 7 , growth factor receptor-bound protein 7-like , GRB7 adapter protein , Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) , epidermal growth factor receptor GRB-7 , growth factor receptor binding protein GRB7 , B47

GENE ID	SPECIES
454637	Pan troglodytes
100392059	Callithrix jacchus
100448630	Pongo abelii
100479529	Ailuropoda melanoleuca
100603732	Nomascus leucogenys
14786	Mus musculus
84427	Rattus norvegicus
100355891	Oryctolagus cuniculus
2886	Homo sapiens
100725019	Cavia porcellus
100513230	Sus scrofa
508847	Bos taurus
491021	Canis lupus familiaris
426597	Gallus gallus
101104589	Ovis aries

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Show all anti-Growth Factor Receptor-Bound Protein 7 (GRB7) Antibodies with Pubmed References

Mouse (Murine) Growth Factor Receptor-Bound Protein 7 (GRB7) interaction partners

Human Growth Factor Receptor-Bound Protein 7 (GRB7) interaction partners

Antigen Summary

Alternative names and synonyms associated with GRB7

Protein level used designations for GRB7