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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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7 | ABIN2426851 | IHC ELISA | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
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Antigen | Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) Antibodies |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This PTPRJ antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), ELISA
Alternatives
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Supplier | Log in to see |
Product Details anti-PTPRJ AntibodyTarget Details PTPRJ Application Details Handling Images |
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Purification | Antigen affinity purification |
Immunogen | Synthetic peptide of human PTPRJ |
Isotype | IgG |
Plasmids, Primers & others | |
Target Details PTPRJProduct Details anti-PTPRJ Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | PTPRJ (PTPRJ Antibody Abstract) |
Background |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA |
Pathways | EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling |
Application DetailsProduct Details anti-PTPRJ Antibody Target Details PTPRJ Handling Images back to top |
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Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
HandlingProduct Details anti-PTPRJ Antibody Target Details PTPRJ Application Details Images back to top |
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Format | Liquid |
Handling Advice | Avoid freeze / thaw cycles. |
Storage | -20 °C/-80 °C |
Storage Comment | Store at -20°C (regular) and -80°C (long term). |
ImagesProduct Details anti-PTPRJ Antibody Target Details PTPRJ Application Details Handling back to top |
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Supplier Images |