DIO1 Proteins
8 Deiodinase, Iodothyronine, Type I (DIO1) Proteins from 5 manufacturers are available on www.antibodies-online.com.
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Deiodinase, Iodothyronine, Type I (DIO1) (AA 1-257) protein (rho-1D4 tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 1-249) protein (rho-1D4 tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 1-61) protein (GST tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 35-125) protein (GST tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 31-257) protein (His tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) Protein Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 1-248) protein (His tag) Protein
Deiodinase, Iodothyronine, Type I (DIO1) (AA 1-248) protein (His tag) Protein
DIO1 Protein Profile
Protein Summary
The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence.
Alternative names and synonyms associated with DIO1
- iodothyronine deiodinase 1 (DIO1) antibody
- type I iodothyronine deiodinase-like (LOC100231867) antibody
- deiodinase, iodothyronine, type I (Dio1) antibody
- deiodinase, iodothyronine type 1 L homeolog (dio1.L) antibody
- iodothyronine deiodinase 1 (dio1) antibody
- 5DI antibody
- cb685 antibody
- D1 antibody
- Deio1 antibody
- DIOI antibody
- ITDI1 antibody
- TXDI1 antibody
- zgc:92323 antibody
Protein level used designations for DIO1
DIOI , thyroxine deiodinase type I (selenoprotein) , type 1 DI , type I iodothyronine deiodinase , type-I 5'-deiodinase , thyroxine deiodinase, type I , 5DI , thyroxine deiodinase type 1 , Type 1 DI , Type-I 5'-deiodinase , deiodinase, iodothyronine, type I , type 1 deiodinase
GENE ID | SPECIES |
---|---|
1733 | Homo sapiens |
100231867 | Taeniopygia guttata |
25430 | Rattus norvegicus |
13370 | Mus musculus |
395940 | Gallus gallus |
403635 | Canis lupus familiaris |
414380 | Sus scrofa |
100101570 | Oryctolagus cuniculus |
493798 | Felis catus |
733447 | Xenopus laevis |
799937 | Danio rerio |