anti-Cow (Bovine) Islet Amyloid Polypeptide antibody for Western Blotting

Recommended Islet Amyloid Polypeptide Antibody (supplied by: Log in to see )

Antigen
Islet Amyloid Polypeptide (IAPP) Antibodies
  • DAP
  • IAP
  • LOC100230121
  • Amylin
  • islet amyloid polypeptide
  • IAPP
  • Iapp
Epitope
N-Term
18
8
5
5
3
2
2
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Rabbit
115
28
19
10
4
4
4
1
1
Host
Rabbit
120
13
Clonality
Polyclonal
Conjugate
Un-conjugated
12
7
5
1
Application
Western Blotting (WB)
69
64
57
24
16
15
12
10
6
5
4
2
2
2
2
1
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Catalog No. ABIN2776959
$ 289.00
Plus shipping costs $45.00

General

Antigen Islet Amyloid Polypeptide (IAPP) Antibodies
Epitope N-Term
(18), (8), (5), (5), (3), (2), (2), (2), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Rabbit
(115), (28), (19), (10), (4), (4), (4), (1), (1)
Host Rabbit
(120), (13)
Clonality
Polyclonal
Conjugate Un-conjugated
(12), (7), (5), (1)
Application Western Blotting (WB)
(69), (64), (57), (24), (16), (15), (12), (10), (6), (5), (4), (2), (2), (2), (2), (1)
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Product details

Target Details Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN978369
Sequence MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV
Predicted Reactivity Cow: 82%, Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 86%
Characteristics This is a rabbit polyclonal antibody against IAPP. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IAPP

Target Details

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Antigen
Alternative Name IAPP (IAPP Antibody Abstract)
Background Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Alias Symbols: AMYLIN, DAP, IAP
Protein Interaction Partner: COL25A1, RAMP2, RAMP1, PDX1, PCSK2, PCSK1,
Protein Size: 89
Molecular Weight 4 kDa
Gene ID 3375
NCBI Accession NM_000415, NP_000406
UniProt P10997
Pathways Hormone Activity, Feeding Behaviour

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 89 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

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Supplier Images
Western Blotting (WB) image for anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibody (ABIN2776959) WB Suggested Anti-IAPP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posit...