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ICMT Products

(Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008].

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Featured ICMT Categories

ICMT Antibodies

High quality antibodies with extensive validation data.

ICMT ELISA Kits

Reliable ELISA kits for a wide range of species.

ICMT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ICMT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6142129
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN389122
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7248446
Quantity 200 μL
Datasheet Datasheet

Recommended ICMT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1152946
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1152947
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1152948
Quantity 96 tests
Datasheet Datasheet

Recommended ICMT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667011
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307337
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307336
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our ICMT products

Nuthalapaty, Lu, Ramin, Nuthalapaty, Ramin, Ramsey: "Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." in: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).

Bergo, Gavino, Hong, Beigneux, McMahon, Casey, Young: "Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf." in: The Journal of clinical investigation, Vol. 113, Issue 4, pp. 539-50, (2004) (PubMed).

Van Dessel, De Busser, Lagrou: "Prenylcysteine carboxymethyltransferase type III activity is decreased in retinoic acid-treated SH-SY5Y neuroblastoma cells." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 5, pp. 477-86, (2002) (PubMed).

Ahmad, Zhang, Zhang, Papharalambus, Alexander: "Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-alpha stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 22, Issue 5, pp. 759-64, (2002) (PubMed).

Synonyms and alternative names related to ICMT

isoprenylcysteine carboxyl methyltransferase (ICMT), isoprenylcysteine carboxyl methyltransferase (Icmt), isoprenylcysteine carboxyl methyltransferase (icmt), isoprenylcysteine carboxyl methyltransferase (Bcen_5417), isoprenylcysteine carboxyl methyltransferase (Acid_0983), isoprenylcysteine carboxyl methyltransferase (Bcenmc03_4825), cobalt-zinc-cadmium resistance protein (RPIC_RS08670), Isoprenylcysteine carboxyl methyltransferase (Mesil_1887), Isoprenylcysteine carboxyl methyltransferase (Slip_1333), Isoprenylcysteine carboxyl methyltransferase (Deba_2487), Isoprenylcysteine carboxyl methyltransferase (Bresu_2161), isoprenylcysteine carboxylmethyltransferase family protein (MPET_RS04760), isoprenylcysteine carboxylmethyltransferase family protein (MPET_RS08305), Isoprenylcysteine carboxyl methyltransferase (Saut_0066), isoprenylcysteine carboxyl methyltransferase (Intca_3523), isoprenylcysteine carboxyl methyltransferase (Deima_2891), Isoprenylcysteine carboxyl methyltransferase (Despr_1203), Isoprenylcysteine carboxyl methyltransferase (Deipr_0831), Isoprenylcysteine carboxyl methyltransferase (Theth_0229), isoprenylcysteine carboxyl methyltransferase S homeolog (icmt.S), 1700008E11Rik, C80758, fcmt, Gm13095, HSTE14, im:6895697, MST098, MSTP098, OTTMUSG00000010406, PCCMT, pcCMT, PCMT, PPMT, STE14, zgc:110258

Protein level used designations for ICMT

  • prenylated protein carboxyl methyltransferase
  • prenylcysteine carboxyl methyltransferase
  • protein-S isoprenylcysteine O-methyltransferase
  • protein-S-isoprenylcysteine O-methyltransferase
  • PPMT
  • farnesyl cysteine carboxyl methyltransferase
  • pcCMT
  • prenylcysteine carboxyl methlytransferase
  • isoprenylcysteine carboxyl methyltransferase
  • Isoprenylcysteine carboxyl methyltransferase
  • FCMT
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