anti-Rat (Rattus) CD25 antibody for ELISA (Detection)

Recommended CD25 Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, alpha (IL2RA) Antibodies
  • CD25
  • IDDM10
  • IL2R
  • TCGFR
  • IL2RAC
  • IL-2RA
  • Il2r
  • Ly-43
  • interleukin 2 receptor subunit alpha
  • interleukin-2 receptor subunit alpha-like
  • interleukin 2 receptor, alpha chain
  • IL2RA
  • Il2ra
  • LOC100222957
Reactivity
Rat (Rattus)
590
482
164
22
19
16
9
8
6
6
5
4
4
4
3
1
Host
Mouse
584
407
151
7
6
3
3
2
Clonality
Monoclonal
Conjugate
This CD25 antibody is conjugated to Alexa Fluor 488
131
117
95
79
29
29
29
24
23
18
16
14
12
12
12
12
12
11
10
10
9
8
8
7
7
6
6
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA (Detection), Flow Cytometry (FACS), Immunohistochemistry (IHC)
937
190
171
151
128
89
88
83
61
30
22
21
19
17
13
12
9
8
7
6
5
5
3
2
1
1
1
1
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Catalog No. ABIN2657370
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General

Antigen Interleukin 2 Receptor, alpha (IL2RA) Antibodies
Reactivity Rat (Rattus)
(590), (482), (164), (22), (19), (16), (9), (8), (6), (6), (5), (4), (4), (4), (3), (1)
Host Mouse
(584), (407), (151), (7), (6), (3), (3), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD25 antibody is conjugated to Alexa Fluor 488
(131), (117), (95), (79), (29), (29), (29), (24), (23), (18), (16), (14), (12), (12), (12), (12), (12), (11), (10), (10), (9), (8), (8), (7), (7), (6), (6), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Detection), Flow Cytometry (FACS), Immunohistochemistry (IHC)
(937), (190), (171), (151), (128), (89), (88), (83), (61), (30), (22), (21), (19), (17), (13), (12), (9), (8), (7), (6), (5), (5), (3), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CD25 Antibody

Target Details CD25 Application Details Handling References for anti-CD25 antibody (ABIN2657370) Images
Purification The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone OX-39
Isotype IgG1 kappa

Target Details CD25

Product Details anti-CD25 Antibody Application Details Handling References for anti-CD25 antibody (ABIN2657370) Images back to top
Antigen
Alternative Name CD25 (IL2RA Antibody Abstract)
Background CD25 is a 55 kD glycoprotein also known as IL-2 receptor α chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains α, β, and γ. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.
Pathways JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation

Application Details

Product Details anti-CD25 Antibody Target Details CD25 Handling References for anti-CD25 antibody (ABIN2657370) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD25 Antibody Target Details CD25 Application Details References for anti-CD25 antibody (ABIN2657370) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-CD25 antibody (ABIN2657370)

Product Details anti-CD25 Antibody Target Details CD25 Application Details Handling Images back to top
Background publications

Dignass, Podolsky: "Interleukin 2 modulates intestinal epithelial cell function in vitro." in: Experimental cell research, Vol. 225, Issue 2, pp. 422-9, 1996

Paterson, Jefferies, Green, Brandon, Corthesy, Puklavec, Williams: "Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts." in: Molecular immunology, Vol. 24, Issue 12, pp. 1281-90, 1988

Tellides, Dallman, Kupiec-Weglinski, Diamantstein, Morris: "Functional blocking of the interleukin-2 receptor (IL-2R) may be important in the efficacy of IL-2R antibody therapy." in: Transplantation proceedings, Vol. 19, Issue 5, pp. 4231-3, 1987

Images

Product Details anti-CD25 Antibody Target Details CD25 Application Details Handling References for anti-CD25 antibody (ABIN2657370) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 2 Receptor, alpha (IL2RA) antibody (Alexa Fluor 488) (ABIN2657370) anti-Interleukin 2 Receptor, alpha (IL2RA) antibody (Alexa Fluor 488)