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|Antigen||Oncostatin M (OSM) Antibodies|
|Conjugate||This Oncostatin M antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
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Product Details anti-Oncostatin M AntibodyTarget Details Oncostatin M Application Details Handling Images
|Immunogen||Oncostatin M antibody was raised in rabbit using highly pure recombinant human oncostatin M as the immunogen.|
|Plasmids, Primers & others|
Target Details Oncostatin MProduct Details anti-Oncostatin M Antibody Application Details Handling Images back to top
|Alternative Name||Oncostatin M (OSM Antibody Abstract)|
|Background||Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi’s sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL6, and CNTF. Human OSM is active on Mouse cells.|
|Molecular Weight||23.9 kDa (predicted detection band MW)|
|Pathways||JAK-STAT Signaling, Negative Regulation of Hormone Secretion|
Application DetailsProduct Details anti-Oncostatin M Antibody Target Details Oncostatin M Handling Images back to top
ELISA: 0.5-2 µg/mL, Inhibition: 0.1-0.175 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Oncostatin M Antibody Target Details Oncostatin M Application Details Images back to top
|Reconstitution||Reconstitute in sterile water to a concentration of > 0.2 mg/mL.|
|Buffer||Lyophilized from 0.5 x PBS, pH 7.4.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|