anti-Mouse (Murine) Oncostatin M antibody for Cell Culture

Recommended Oncostatin M Antibody (supplied by: Log in to see )

Antigen
Oncostatin M (OSM) Antibodies
  • OSM
  • OncoM
  • oncostatin M
  • OSM
  • Osm
Epitope
AA 25-206
13
10
9
8
7
7
5
5
5
4
4
4
3
2
2
2
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
187
49
24
2
Host
Rabbit
138
66
16
3
1
Clonality
Polyclonal
Conjugate
This Oncostatin M antibody is un-conjugated
23
11
11
7
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
Application
Cell Culture (CC), Western Blotting (WB)
162
90
53
46
26
20
14
10
9
6
4
4
4
2
2
1
1
1
1
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Catalog No. ABIN5519048
$ 240.00
Plus shipping costs $45.00

General

Antigen Oncostatin M (OSM) Antibodies
Epitope AA 25-206
(13), (10), (9), (8), (7), (7), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(187), (49), (24), (2)
Host Rabbit
(138), (66), (16), (3), (1)
Clonality
Polyclonal
Conjugate This Oncostatin M antibody is un-conjugated
(23), (11), (11), (7), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Cell Culture (CC), Western Blotting (WB)
(162), (90), (53), (46), (26), (20), (14), (10), (9), (6), (4), (4), (4), (2), (2), (1), (1), (1), (1)
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Product Details anti-Oncostatin M Antibody

Target Details Oncostatin M Application Details Handling Images
Purpose Rabbit IgG polyclonal antibody for Oncostatin M detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Oncostatin M detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
Gene Name: oncostatin M
Protein Name: Oncostatin-M
Purification Immunogen affinity purified.
Immunogen E. coli-derived mouse Oncostatin M recombinant protein (Position: N25-R206).
Isotype IgG
Plasmids, Primers & others

Target Details Oncostatin M

Product Details anti-Oncostatin M Antibody Application Details Handling Images back to top
Antigen
Alternative Name Osm (OSM Antibody Abstract)
Background OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. It has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.

Synonyms: Oncostatin-M, OSM, Osm
Gene ID 18413
UniProt P53347
Pathways JAK-STAT Signaling, Negative Regulation of Hormone Secretion

Application Details

Product Details anti-Oncostatin M Antibody Target Details Oncostatin M Handling Images back to top
Application Notes Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions For Research Use only

Handling

Product Details anti-Oncostatin M Antibody Target Details Oncostatin M Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Images

Product Details anti-Oncostatin M Antibody Target Details Oncostatin M Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Oncostatin M (OSM) (AA 25-206) antibody (ABIN5519048) Western blot analysis of Oncostatin M using anti-Oncostatin M antibody . Electrophore...