anti-Human Serotonin Receptor 2B antibody for Immunohistochemistry

Recommended Serotonin Receptor 2B Antibody (supplied by: Log in to see )

Antigen
Serotonin Receptor 2B (HTR2B) Antibodies
  • 5-HT2B
  • 5HT2B
  • 5htr2b
  • HTR2B
  • 5ht2b
  • zgc:194094
  • zgc:194119
  • AJ012488
  • AV377389
  • 5-HT(2B)
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • 5-hydroxytryptamine (serotonin) receptor 2B
  • HTR2B
  • htr2b
  • Htr2b
Epitope
AA 1-58
12
12
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
109
35
33
3
2
2
2
2
1
1
Host
Mouse
107
4
Clonality
Monoclonal
Conjugate
This Serotonin Receptor 2B antibody is un-conjugated
3
3
3
3
3
3
3
3
3
3
3
2
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
52
33
31
25
20
19
5
3
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN967504
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.199822 ABIN1534243 IF IHC ELISA WB Rabbit IgG AA 261-310 Log in to see Polyclonal 0
9.199822 ABIN4276881 IHC IHC (p) Rabbit IgG Log in to see Polyclonal 1
9.199822 ABIN1048268 IHC IHC (p) Rabbit N-Term Log in to see Polyclonal 0
9.199822 ABIN2879284 ELISA IF IHC IHC (p) WB Rabbit IgG AA 15-64 Log in to see Polyclonal 0
9.199822 ABIN1048267 IHC IHC (p) Rabbit Cytoplasmic Domain Log in to see Polyclonal 0
9.199822 ABIN1048266 IHC IHC (p) Rabbit Extracellular Domain Log in to see Polyclonal 0
9.199822 ABIN2421129 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN2889845 ELISA IF IHC IHC (p) WB Rabbit IgG AA 261-310 Log in to see Polyclonal 0
1 ABIN1876871 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1454115 IHC ELISA WB Rabbit IgG AA 233-282 Log in to see Polyclonal 0
1 ABIN2884776 IHC ELISA WB Rabbit IgG AA 233-282 Log in to see Polyclonal 0
1 ABIN2881212 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1873110 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2697509 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2286735 IHC Rabbit 2nd Extracellular Domain Log in to see Polyclonal 0
1 ABIN2286732 IHC Rabbit 2nd Extracellular Domain Log in to see Polyclonal 0
1 ABIN2286734 IHC Rabbit N-Term Log in to see Polyclonal 0
1 ABIN2286733 IHC Rabbit Log in to see Polyclonal 0
1 ABIN2427711 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2976164 IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Serotonin Receptor 2B (HTR2B) Antibodies
Epitope AA 1-58
(12), (12), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(109), (35), (33), (3), (2), (2), (2), (2), (1), (1)
Host Mouse
(107), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Serotonin Receptor 2B antibody is un-conjugated
(3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(52), (33), (31), (25), (20), (19), (5), (3), (2), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-Serotonin Receptor 2B Antibody

Target Details Serotonin Receptor 2B Application Details Handling References for anti-Serotonin Receptor 2B antibody (ABIN967504) Images
Brand BD Pharmingen™
Cross-Reactivity Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human 5HT[2B]R (aa. 1-58) fusion protein
Clone A72-1
Isotype IgG1, kappa

Target Details Serotonin Receptor 2B

Product Details anti-Serotonin Receptor 2B Antibody Application Details Handling References for anti-Serotonin Receptor 2B antibody (ABIN967504) Images back to top
Antigen
Alternative Name Serotonin Receptor 5-HT 2BR (HTR2B Antibody Abstract)
Background Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor, plays an important role in regulating diverse biological processes in the central and peripheral nervous systems, the cardiovascular system and the gastrointestinal systems. The different functions of serotonin are thought to be mediated through specific receptors. Physiological, biochemical, and pharmacological studies have defined at least fourteen serotonin receptors. The fourteen receptors are grouped in seven subtypes according to operational, structural, and transductional properties. The 5-HT2 receptors (5 -HT[2A]R, 5-HT[2B]R, an d 5-HT[2C]R) may be considered as prototypes for the study of serotonin receptors . Their functions are mediated by the second messenger inositol polyphosphate in a G-protein coupled pathway. They are expressed in diverse tissues including brain, vascular smooth muscles and platelets. The 5-HT[2A]R-mRNAs have been found in only a few areas of the brain, including the frontal cortex, piriform cortex, ventro-caudal part of CA3, motor cranial nerve nuclei in the brainstem, and the ventral horn of the spinal cord. The 5-HT[2C]R mRNA has been found at high levels in many parts of the brain including retrosplenial piriform and entorhinal cortex, anterior olfactory nucleus, substantia nigra pars compacta, several brainstem nuclei and the whole grey matter of the spinal cord. The 5-HT[2B]R was cloned in stomach fundus, where it is abundantly expressed.
Molecular Weight 45-55 kDa
Pathways JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Handling References for anti-Serotonin Receptor 2B antibody (ABIN967504) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details References for anti-Serotonin Receptor 2B antibody (ABIN967504) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-Serotonin Receptor 2B antibody (ABIN967504)

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details Handling Images back to top
Product cited in:

Duxon, Flanigan, Reavley, Baxter, Blackburn, Fone: "Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system." in: Neuroscience, Vol. 76, Issue 2, pp. 323-9, 1997

Saudou, Hen: "5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates." in: Neurochemistry international, Vol. 25, Issue 6, pp. 503-32, 1995

Pompeiano, Palacios, Mengod: "Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors." in: Brain research. Molecular brain research, Vol. 23, Issue 1-2, pp. 163-78, 1994

Humphrey, Hartig, Hoyer: "A proposed new nomenclature for 5-HT receptors." in: Trends in pharmacological sciences, Vol. 14, Issue 6, pp. 233-6, 1993

Foguet, Hoyer, Pardo, Parekh, Kluxen, Kalkman, Stühmer, Lübbert: "Cloning and functional characterization of the rat stomach fundus serotonin receptor." in: The EMBO journal, Vol. 11, Issue 9, pp. 3481-7, 1992

Images

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details Handling References for anti-Serotonin Receptor 2B antibody (ABIN967504) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (ABIN967504) Immunohistochemical staining of neurons in rat brain (hippocampus) (first panel). A z...
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (ABIN967504) Western blot analysis for 5-HT2BR (second panel). A rat whole brain lysate was probed...
Immunohistochemistry (IHC) image for anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (ABIN967504) anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (Image 3)
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (ABIN967504) anti-Serotonin Receptor 2B (HTR2B) (AA 1-58) antibody (Image 4)