NTRK3 ELISA Kit
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- Target See all NTRK3 ELISA Kits
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Binding Specificity
- AA 32-429
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Reactivity
- Mouse
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 156 pg/mL - 10000 pg/mL
- Minimum Detection Limit
- 156 pg/mL
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse TRKC. 96wells/kit, with removable strips.
- Brand
- PicoKine™
- Sample Type
- Cell Culture Supernatant, Cell Lysate
- Analytical Method
- Quantitative
- Specificity
- Expression system for standard: NSO, Immunogen sequence: C32-T429
- Sensitivity
- < 10 pg/mL
- Components
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
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- Assay Time
- 25 min
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
-
- Target See all NTRK3 ELISA Kits
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- Alternative Name
- Ntrk3 (NTRK3 Products)
- Synonyms
- TRKC ELISA Kit, gp145(trkC) ELISA Kit, trkC ELISA Kit, AW125844 ELISA Kit, Ntrk3_tv3 ELISA Kit, TrkC ELISA Kit, neurotrophic receptor tyrosine kinase 3 ELISA Kit, neurotrophic tyrosine kinase, receptor, type 3 ELISA Kit, NTRK3 ELISA Kit, Ntrk3 ELISA Kit
- Background
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Synonyms: NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, Ntrk3, TrkC
Tissue Specificity: Isoform 2 expression is restricted to specific areas in adult brain. Isoform 3 transcripts are readily detected early during embryogenesis and are expressed predominantly in adult brain and gonads.
Background: NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, it mapped the NTRK3 gene to 15q24-q25. TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain, in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, 5 miRNAs regulate the truncated form of NTRK3.
Cellular Localisation: Membrane, Single-pass type I membrane protein. - UniProt
- Q6VNS1
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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