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LDLR Antibodies

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
LDLR antibody  (AA 22-150) LDLR antibody  (AA 22-150) LDLR antibody (AA 22-150) (ABIN5542334)

LDLR Reactivity: Human ELISA, FACS, ICC, IHC, WB Host: Mouse Monoclonal 1B10H10 unconjugated

LDLR antibody  (C-Term) LDLR antibody  (C-Term) LDLR antibody (C-Term) (ABIN7268296)

KO Validated LDLR Reactivity: Human IF, IHC, WB Host: Rabbit Polyclonal unconjugated

LDLR antibody  (AA 781-860) LDLR antibody  (AA 781-860) LDLR antibody (AA 781-860) (ABIN672111)

LDLR Reactivity: Human, Mouse, Rat, Hamster, Plant ELISA, FACS, IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated

LDLR Antibodies by Grade

Find LDLR Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LDLR Antibodies by Reactivity

Find LDLR Antibodies for a variety of species such as anti-Human LDLR, anti-Mouse LDLR, anti-Rat LDLR. The species listed below are among those available. Click on a link to go to the corresponding products.

LDLR Antibodies by Application

Find LDLR Antibodies validated for a specific application such as WB, FACS, ELISA, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LDLR Antibodies by Host

Find LDLR Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

LDLR Antibodies by Binding Specificity

Find LDLR Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LDLR Antibodies by Clonality

Find available monoclonal or polyclonal LDLR Antibodies. Click on a link to go to the corresponding products.

LDLR Antibodies by Clone

Find LDLR Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

LDLR Antibodies by Conjugate

Find LDLR Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LDLR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (5)
Cat. No. ABIN5542334
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (5)
Cat. No. ABIN7268296
Quantity 100 μL
Datasheet Datasheet
Reactivity Hamster, Human, Mouse, Plant, Rat
Application ELISA, FACS, IF (p), IHC (p), WB
Validations
  • (5)
  • (3)
Cat. No. ABIN672111
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IF, IHC
Validations
  • (4)
Cat. No. ABIN7127599
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN7249770
Quantity 200 μL
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (4)
Cat. No. ABIN5013888
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • (3)
Cat. No. ABIN7432991
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, IP, WB
Validations
  • (3)
Cat. No. ABIN7440485
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6656143
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3031637
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (2)
Cat. No. ABIN561655
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, WB
Validations
  • (2)
Cat. No. ABIN652907
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ICC, IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1909537
Quantity 1 each
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2489186
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN500146
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our LDLR Antibodies

Moessinger, Nilsson, Muhl, Zeitelhofer, Heller Sahlgren, Skogsberg, Eriksson: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." in: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).

Lebeau, Platko, Al-Hashimi, Byun, Lhoták, Holzapfel, Gyulay, Igdoura, Cool, Trigatti, Seidah, Austin: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).

Khoshnejad, Patel, Wojtak, Kudchodkar, Humeau, Lyssenko, Rader, Muthumani, Weiner: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Silva, Lütjohann, Hamid, Velasquez, Kerner, Larrazabal, Failing, Hermosilla, Taubert: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).

Xu, Xu, Xu, Yin, Zhang: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." in: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).

Fischer, Albers, Krott, Hoffzimmer, Heine, Schmale, Scheja, Gordts, Heeren: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." in: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).

Riad, Zeng, Weng, Winters, Xu, Makvandi, Metz, Carlin, Mach: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." in: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).

Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

Sirois, Chrétien, Mbikay: "Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol." in: Molecular genetics and metabolism reports, Vol. 10, pp. 11-17, (2017) (PubMed).

Aliases for LDLR Antibodies

low density lipoprotein receptor a (ldlra) Antibodies
low density lipoprotein receptor (LDLR) Antibodies
low density lipoprotein receptor (Ldlr) Antibodies
FH Antibodies
FHC Antibodies
Hlb301 Antibodies
LDLA Antibodies
LDLCQ2 Antibodies
LDLRA Antibodies
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