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anti-Human MDFI Antibodies:
anti-Mouse (Murine) MDFI Antibodies:
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Human Polyclonal MDFI Primary Antibody for ELISA - ABIN4231814
Ma, Rundle, Jacks, Koch, Downs, Tsiokas: Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1. in The Journal of biological chemistry 2003
MDFI was significantly hypermethylated in colorectal cancer tissues when compared with adjacent normal colorectal tissues.
I-mfa domain proteins may be involved in their oncogenic functions by negatively regulating their transcriptional activities.
I-mfa functions as a molecular switch to suppress the store dependence of TRPC1
These results suggest that the physical and functional interaction between Zic and I-mfa proteins can play a role in the vertebrate development.
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
myoD family inhibitor
, MyoD family inhibitor
, inhibitor of MyoD family a
, myogenic repressor I-mf