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Metabotropic Glutamate Receptor 4 Products

(Glutamate Receptor, Metabotropic 4 (GRM4))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Featured Metabotropic Glutamate Receptor 4 Categories

Metabotropic Glutamate Receptor 4 Antibodies

High quality antibodies with extensive validation data.

Metabotropic Glutamate Receptor 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Metabotropic Glutamate Receptor 4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Metabotropic Glutamate Receptor 4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN6261989
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rabbit
Application IHC, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN1048935
Quantity 50 μg
Datasheet Datasheet
Reactivity Chicken, Human, Monkey, Mouse, Rat
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7295826
Quantity 100 μL
Datasheet Datasheet

Recommended Metabotropic Glutamate Receptor 4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381314
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN1749408
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1772983
Quantity 96 tests
Datasheet Datasheet

Recommended Metabotropic Glutamate Receptor 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123399
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081011
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135628
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Metabotropic Glutamate Receptor 4 products

Wichert, Stege, Midorikawa, Holm, Lage: "Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells." in: Oncogene, Vol. 23, Issue 4, pp. 945-55, (2004) (PubMed).

Boily, Saikali, Sinnett: "Methylation analysis of the glypican 3 gene in embryonal tumours." in: British journal of cancer, Vol. 90, Issue 8, pp. 1606-11, (2004) (PubMed).

Nakatsura, Kageshita, Ito, Wakamatsu, Monji, Ikuta, Senju, Ono, Nishimura: "Identification of glypican-3 as a novel tumor marker for melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 19, pp. 6612-21, (2004) (PubMed).

Synonyms and alternative names related to Metabotropic Glutamate Receptor 4

glutamate metabotropic receptor 4 (GRM4), glutamate receptor, metabotropic 4 (Grm4), glutamate metabotropic receptor 4 (Grm4), glutamate receptor, metabotropic 4 (GRM4), GPRC1D, Gprc1d, mGlu4, MGLUR4, mGluR4

Protein level used designations for Metabotropic Glutamate Receptor 4

  • metabotropic glutamate receptor 4
  • G protein-coupled receptor GRM4
  • G protein-coupled receptor, family C, group 1, member D
  • mGluR4
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