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This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
ErbB-3 binding protein 1
, ErbB3-binding protein Ebp1
, cell cycle protein p38-2G4 homolog
, erbB3-binding protein 1
, proliferation-associated protein 2G4
, ErbB3-binding protein 1
, proliferation-associated 2G4, 38kDa
, proliferation-associated protein 2G4-like
, similar to proliferation-associated 2G4, 38kD
, IRES-specific cellular trans-acting factor 45 kDa
, proliferation-associated 2G4, 38kD
, proliferation-associated protein 1
, protein p38-2G4