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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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11.706686 | ABIN2707591 | IC IF IHC WB | Rabbit | N-Term, pSer23 | Log in to see | Polyclonal | 0 | |||
11.706686 | ABIN442231 | ICC IF IHC (p) IHC WB | Rabbit | IgG | C-Term | Log in to see | Polyclonal | 0 | ||
11.706686 | ABIN1870261 | IF | Rabbit | IgG | pTyr199 | Log in to see | Polyclonal | 0 | ||
11.706686 | ABIN349146 | IF | Rabbit | IgG | pTyr199 | Log in to see | Polyclonal | 0 | ||
11.706686 | ABIN349358 | IF | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN401636 | IF | Rabbit | Tyr199 | Log in to see | Polyclonal | 1 | |||
1 | ABIN218607 | IF IHC (p) IP ELISA WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN5689462 | IF WB | Rabbit | AA 197-201 | Log in to see | Polyclonal | 0 | |||
1 | ABIN363020 | IF | Rabbit | IgG | AA 197-201 | Log in to see | Polyclonal | 2 | ||
1 | ABIN2470337 | IF IP IHC ELISA WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN595887 | IF | Rabbit | IgG | pTyr199 | Log in to see | Polyclonal | 0 | ||
1 | ABIN5663753 | IF WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN595886 | IF | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN2882715 | IF | Rabbit | IgG | pTyr199 | Log in to see | Polyclonal | 0 | ||
1 | ABIN2880093 | IF IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN5674477 | IF WB | Rabbit | AA 197-201 | Log in to see | Polyclonal | 0 | |||
1 | ABIN5674539 | IF | Rabbit | pTyr199 | Log in to see | Polyclonal | 0 | |||
1 | ABIN4368426 | IF | Rabbit | pTyr199 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Human, Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This IKBKB antibody is un-conjugated Alternatives |
Application |
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-IKBKB AntibodyTarget Details IKBKB Application Details Handling Images |
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Cross-Reactivity | Rhesus Monkey |
Cross-Reactivity (Details) | Rhesus Monkey (100 %) |
Characteristics |
Rabbit Polyclonal antibody to IKK beta (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) IKK beta antibody |
Purification | Purified by antigen-affinity chromatography. |
Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human IKK beta. The exact sequence is proprietary. |
Isotype | IgG |
Target Details IKBKBProduct Details anti-IKBKB Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | IKK beta (IKBKB Antibody Abstract) |
Background |
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).[supplied by OMIM] Cellular Localization: Cytoplasm |
Molecular Weight | 87 kDa |
Gene ID | 3551 |
Pathways | NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades |
Application DetailsProduct Details anti-IKBKB Antibody Target Details IKBKB Handling Images back to top |
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Application Notes | Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000* |
Comment |
Positive Control: A431 , PC-12 , DDDDK-human IKBKB-transfected 293T |
Restrictions | For Research Use only |
HandlingProduct Details anti-IKBKB Antibody Target Details IKBKB Application Details Images back to top |
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Format | Liquid |
Concentration | 0.41 mg/mL |
Buffer | 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative. |
Preservative | Thimerosal (Merthiolate) |
Precaution of Use | This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
ImagesProduct Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling back to top |
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Supplier Images |
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