anti-Cow (Bovine) Insulin antibody for Functional Studies

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Human, Pig (Porcine), Cow (Bovine)
988
495
381
373
235
188
47
9
7
6
5
5
4
2
2
1
1
1
1
1
1
1
Host
Mouse
818
196
50
16
3
1
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
53
43
38
28
27
22
22
19
17
17
15
14
14
14
14
14
14
14
9
9
9
8
8
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
Application
Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), ELISA
500
389
279
278
251
235
189
117
106
67
66
30
26
23
21
8
6
6
5
4
4
3
2
1
1
1
1
1
1
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Catalog No. ABIN94408
$ 253.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN206973 BR ELISA Func ICC IHC IHC (p) Neut RIA Mouse IgG1 Log in to see IN-05 0
1 ABIN111965 EIA Func IHC (p) RIA Mouse IgG1 Log in to see IN-05 1
1 ABIN3200648 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05 0
1 ABIN3200649 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05 0
1 ABIN3200650 ELISA Func ICC IHC (p) RIA Mouse IgG1 Log in to see IN-05 0
1 ABIN2749217 Func ICC IHC (p) RIA ELISA Mouse IgG1 Log in to see IN-05 0

General

Antigen Insulin (INS) Antibodies
Reactivity Human, Pig (Porcine), Cow (Bovine)
(988), (495), (381), (373), (235), (188), (47), (9), (7), (6), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(818), (196), (50), (16), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(53), (43), (38), (28), (27), (22), (22), (19), (17), (17), (15), (14), (14), (14), (14), (14), (14), (14), (9), (9), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
Application Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), ELISA
(500), (389), (279), (278), (251), (235), (189), (117), (106), (67), (66), (30), (26), (23), (21), (8), (6), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN94408) Images
Specificity The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma.
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Immunogen Porcine insulin.
Clone IN-05
Isotype IgG1
Plasmids, Primers & others

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN94408) Images back to top
Antigen
Alternative Name INS (INS Antibody Abstract)
Background Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN94408) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN94408) Images back to top
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-Insulin antibody (ABIN94408)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Product cited in:

Horejsí, Hilgert, Kristofová, Satayalai: "Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor." in: Immunology letters, Vol. 8, Issue 5, pp. 279-83, 1985