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Insulin Antibodies

(Insulin (INS))
Insulin, a peptide hormone synthesized within the beta cells of the Islets of Langerhans in the pancreas, serves as a pivotal orchestrator in the intricate regulation of blood glucose concentrations. Operating through a series of intricate cellular mechanisms, insulin exerts its influence on glucose metabolism by modulating cellular glucose uptake, storage, and utilization.

Insulin antibodies are essential tools for studying insulin-related processes and investigating conditions like diabetes. Here are some primary applications for insulin research antibodies:

  • Immunohistochemistry (IHC) and Immunofluorescence (IF): Insulin antibodies are used to visualize the distribution and localization of insulin in tissues. IHC and IF techniques allow researchers to identify insulin-producing cells within pancreatic islets and study changes in insulin expression in response to different physiological or pathological conditions.
  • Cell Signaling Studies: Insulin is a potent signaling molecule that regulates glucose metabolism and cellular responses. Insulin antibodies are utilized to investigate insulin signaling pathways, including receptor activation, downstream kinase cascades, and transcriptional responses.
  • Pharmacological Studies: In drug development and testing, insulin antibodies are used to assess the effects of potential therapeutics on insulin expression, secretion, and signaling. This information is crucial for developing new treatments for diabetes and related conditions.
  • Immunoassays: Insulin antibodies are used in various immunoassays, such as enzyme-linked immunosorbent assays (ELISAs), to quantify insulin levels in biological samples like blood and tissue homogenates. These assays are valuable for clinical diagnosis and research studies.
  • Cell Culture and In Vitro Studies: In vitro studies often involve the use of insulin antibodies to modulate insulin signaling in cultured cells and assess the outcomes on cellular metabolism and growth.
Insulin antibody  (AA 1-110) Insulin antibody  (AA 1-110) Insulin antibody (AA 1-110) (ABIN3022885)

INS Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated

Insulin antibody  (AA 46-59) Insulin antibody  (AA 46-59) Insulin antibody (AA 46-59) (ABIN724265)

INS Reactivity: Mouse, Rat ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

Insulin antibody Insulin antibody Insulin antibody (ABIN7267886)

INS Reactivity: Human IHC, WB, IF Host: Rabbit Monoclonal unconjugated

Insulin Antibodies by Reactivity

Find Insulin Antibodies for a variety of species such as anti-Human Insulin, anti-Mouse Insulin, anti-Pig Insulin. The species listed below are among those available. Click on a link to go to the corresponding products.

Insulin Antibodies by Application

Find Insulin Antibodies validated for a specific application such as WB, ELISA, FACS, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Insulin Antibodies by Host

Find Insulin Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Insulin Antibodies by Binding Specificity

Find Insulin Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Insulin Antibodies by Clonality

Find available monoclonal or polyclonal Insulin Antibodies. Click on a link to go to the corresponding products.

Insulin Antibodies by Clone

Find Insulin Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Insulin Antibodies by Conjugate

Find Insulin Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Insulin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN3022885
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro)
Validations
  • (1)
  • (4)
Cat. No. ABIN724265
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (5)
Cat. No. ABIN7267886
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (4)
Cat. No. ABIN7429844
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IHC, WB, IP, ICC
Validations
  • (4)
Cat. No. ABIN7429847
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (4)
Cat. No. ABIN6254161
Quantity 600 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7260153
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (3)
Cat. No. ABIN7429841
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN7425869
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow
Application IHC, WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN7429853
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7127574
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB, IP
Validations
  • (2)
Cat. No. ABIN129507
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Pig, Rabbit
Application IHC, StM
Validations
  • (2)
Cat. No. ABIN6939797
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Pig, Rabbit
Application IHC, StM
Validations
  • (2)
Cat. No. ABIN6939798
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Pig
Application IHC, IF, IHC (p), FACS, ISt, StM
Validations
  • (2)
Cat. No. ABIN6939789
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Insulin Antibodies

Chen, Ren, Zhou, Deng, Hu, Zhang, Li: "HWL-088, a new potent free fatty acid receptor 1 (FFAR1) agonist, improves glucolipid metabolism and acts additively with metformin in ob/ob diabetic mice." in: British journal of pharmacology, Vol. 177, Issue 10, pp. 2286-2302, (2021) (PubMed).

Zhao, Wang, Zhu, Xia, Zhang, Wang, Zhang, Xu, Chen, Jiang, Liu, Wu, Wu, Zhang, Bai, Fotina, Hu: "The Antimicrobial Peptide Mastoparan X Protects Against Enterohemorrhagic Escherichia coli O157:H7 Infection, Inhibits Inflammation, and Enhances the Intestinal Epithelial Barrier." in: Frontiers in microbiology, Vol. 12, pp. 644887, (2021) (PubMed).

Meesaragandla, Karanth, Janke, Delcea: "Biopolymer-coated gold nanoparticles inhibit human insulin amyloid fibrillation." in: Scientific reports, Vol. 10, Issue 1, pp. 7862, (2020) (PubMed).

Fang, Weng, Li, Tao, Mai, Liu, Lu, Lai, Duan, Alvarez, Arvan, Wynshaw-Boris, Li, Pei, Jin, Li: "Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key ��-Cell-Specific Disease Genes." in: Cell reports, Vol. 26, Issue 11, pp. 3132-3144.e7, (2019) (PubMed).

Xu, Huang, Guo, Xiong, Zhu, Xu, Lu, Li, Wan, Lu, Wang: "microRNA-690 regulates induced pluripotent stem cells (iPSCs) differentiation into insulin-producing cells by targeting Sox9." in: Stem cell research & therapy, Vol. 10, Issue 1, pp. 59, (2019) (PubMed).

Chen, Zeng, Liu, Guo, Zhang, Chen, Lin, Wen, Zhao, Lin, Gao: "Adropin deficiency worsens HFD-induced metabolic defects." in: Cell death & disease, Vol. 8, Issue 8, pp. e3008, (2018) (PubMed).

Zheng, Cao, Zhang, Yan, Xu, Zhao, Zhu, Zhang, Li, Zhu: "Abnormal gene methylation during embryonic development after preimplantation genetic testing increases risk of liver-derived insulin resistance." in: Annals of the New York Academy of Sciences, (2018) (PubMed).

Cao, Kakar, Hossen, Wu, Chen: "Sustained epidermal powder drug delivery via skin microchannels." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 249, pp. 94-102, (2017) (PubMed).

Dooley, Tian, Schonefeldt, Delghingaro-Augusto, Garcia-Perez, Pasciuto, Di Marino, Carr, Oskolkov, Lyssenko, Franckaert, Lagou, Overbergh, Vandenbussche, Allemeersch, Chabot-Roy, Dahlstrom, Laybutt et al.: "Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes. ..." in: Nature genetics, Vol. 48, Issue 5, pp. 519-27, (2017) (PubMed).

Zöllner, Jouni, Panzer, Khadour, Janzen, Wesche, Ten Berg, Schellong, Heinken, Greinacher, Bakchoul: "Platelet activation in the presence of neutral protamine Hagedorn insulin: a new feature of antibodies against protamine/heparin complexes." in: Journal of thrombosis and haemostasis : JTH, (2016) (PubMed).

Aliases for Insulin Antibodies

insulin (INS) Antibodies
insulin (INS-IGF2) Antibodies
insulin (ins) Antibodies
insulin (Ins) Antibodies
insulin precursor (PIN) Antibodies
insulin II (Ins2) Antibodies
preproinsulin (ins) Antibodies
insulin L homeolog (ins.L) Antibodies
insulin S homeolog (ins.S) Antibodies
AA986540 Antibodies
IDDM2 Antibodies
igf2-A Antibodies
ILPR Antibodies
ins Antibodies
Ins-2 Antibodies
ins-a Antibodies
ins-b Antibodies
ins1 Antibodies
ins1-a Antibodies
InsII Antibodies
Insulin Antibodies
IRDN Antibodies
Mody Antibodies
Mody4 Antibodies
MODY10 Antibodies
proinsulin Antibodies
xins Antibodies
zgc:109842 Antibodies
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