anti-Ferret Insulin antibody for Immunohistochemistry (Frozen Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • insulin-like
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • Ins2
  • LOC100060077
Reactivity
Ferret, Human, Pig (Porcine), Rat (Rattus)
965
396
302
283
261
121
49
6
6
6
5
5
4
2
1
1
1
1
1
1
1
1
Host
Rabbit
843
182
54
25
3
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
57
42
41
28
28
27
23
23
18
17
17
17
17
17
17
16
16
12
11
11
11
11
11
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
622
371
248
234
208
204
161
142
71
66
40
27
18
11
9
8
8
7
5
4
3
3
3
2
2
2
1
1
1
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Catalog No. ABIN113504
$ 467.50
Plus shipping costs $45.00

General

Antigen Insulin (INS) Antibodies
Reactivity Ferret, Human, Pig (Porcine), Rat (Rattus)
(965), (396), (302), (283), (261), (121), (49), (6), (6), (6), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(843), (182), (54), (25), (3), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(57), (42), (41), (28), (28), (27), (23), (23), (18), (17), (17), (17), (17), (17), (17), (16), (16), (12), (11), (11), (11), (11), (11), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(622), (371), (248), (234), (208), (204), (161), (142), (71), (66), (40), (27), (18), (11), (9), (8), (8), (7), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN113504) Images
Specificity The antibody detects Insulin which is produced by the B-cells of the pancreatic islets. Antibody BP5053 can be used for the diagnosis of pancreatic B-cell tumors. Antigen localization: cytoplasm, extracellular.
Purification Serum
Immunogen Porcine insulin

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN113504) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN113504) Images back to top
Application Notes ELISA. Immunohistochemistry on frozen and paraffin sections: proteolytic treatment is notrequired, optimal results have been obtained by using the autoclave or microwave retrievalmethod (with citrate buffer). For immunohistochemistry dilute 1: 50 - 1: 100 (with PBS or TBS immediately before use),based on the indirect method, with a normal ABC method the dilution can be up to 5xhigher when using the microwave retrieval method. Recommended positive control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN113504) Images back to top
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN113504)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Luts, Sundler: "Peptide-containing nerve fibers in the respiratory tract of the ferret." in: Cell and tissue research, Vol. 258, Issue 2, pp. 259-67, 1990