anti-Human Insulin antibody for Western Blotting

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Human
718
278
252
231
186
108
10
8
7
7
6
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
541
209
50
9
4
2
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
38
29
27
15
14
13
7
7
7
7
7
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
2
2
1
Application
Western Blotting (WB)
334
231
193
168
168
143
107
66
57
33
32
32
23
23
21
7
5
4
4
4
3
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN3020884
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
21.641695 ABIN3022885 IHC WB Rabbit IgG Log in to see Polyclonal 1
19.8439 ABIN1873240 IHC WB Rabbit IgG Log in to see Polyclonal 0
19.297794 ABIN129507 IP IHC ELISA WB Mouse IgG Log in to see 2D11-H5 0
17.141695 ABIN3023553 WB Rabbit IgG pTyr1361 Log in to see 0
17.141695 ABIN3023559 WB Rabbit IgG pTyr1189 Log in to see Polyclonal 0
17.141695 ABIN6254161 WB Goat IgG Log in to see Polyclonal 0
13.297794 ABIN4901805 ELISA WB Rabbit IgG AA 30-70 Log in to see Polyclonal 0
13.297794 ABIN5619984 WB Rabbit Center Log in to see Polyclonal 0
13.297794 ABIN5619985 WB Rabbit Center Log in to see Polyclonal 0
13.297794 ABIN3023556 WB Rabbit IgG pTyr1185 Log in to see Polyclonal 0
13.297794 ABIN3023565 WB Rabbit IgG pTyr1355 Log in to see Polyclonal 0
13.297794 ABIN3023562 WB Rabbit IgG pTyr1190 Log in to see Polyclonal 0
13.297794 ABIN5621390 WB Rabbit Log in to see Polyclonal 0
13.297794 ABIN2144376 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
13.297794 ABIN2144401 WB Rabbit IgG Log in to see Polyclonal 0
12.184746 ABIN4326017 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
10.843901 ABIN5530710 IHC (p) WB Rabbit Ig Fraction AA 21-52, N-Term Log in to see Polyclonal 0
9.343901 ABIN6672147 WB Rabbit IgG Log in to see Polyclonal 1
9.343901 ABIN6673370 IHC WB Rabbit IgG Log in to see Polyclonal 1
7.8439007 ABIN6262605 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Insulin (INS) Antibodies
Reactivity Human
(718), (278), (252), (231), (186), (108), (10), (8), (7), (7), (6), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(541), (209), (50), (9), (4), (2), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(38), (29), (27), (15), (14), (13), (7), (7), (7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (1)
Application Western Blotting (WB)
(334), (231), (193), (168), (168), (143), (107), (66), (57), (33), (32), (32), (23), (23), (21), (7), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN3020884) Images
Purification Affinity purification
Immunogen Recombinant protein of human Insulin Receptor beta
Isotype IgG
Plasmids, Primers & others

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN3020884) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Type I insulin-like growth factor receptor (IGF-IR) is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues. Receptor autophosphorylation follows binding of the IGF-I and IGF-II ligands. Three tyrosine residues within the kinase domain (Tyr1131, Tyr1135, and Tyr1136) are the earliest major autophosphorylation sites. Phosphorylation of these three tyrosine residues is necessary for kinase activation. Insulin receptors (IRs) share significant structural and functional similarity with IGF-I receptors, including the presence of an equivalent tyrosine cluster (Tyr1146/1150/1151) within the kinase domain activation loop. Tyrosine autophosphorylation of IRs is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151, while full kinase activation requires triple tyrosine phosphorylation.
Synonyms: INSR, CD220, HHF5
Gene ID 3643
UniProt P06213
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN3020884) Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN3020884) Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

References for anti-Insulin antibody (ABIN3020884)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Product cited in:

Zheng, Cao, Zhang, Yan, Xu, Zhao, Zhu, Zhang, Li, Zhu: "Abnormal gene methylation during embryonic development after preimplantation genetic testing increases risk of liver-derived insulin resistance." in: Annals of the New York Academy of Sciences, 2018 Method employed by authors: Western Blotting (WB)

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN3020884) back to top
Supplier Images
Western Blotting (WB) image for anti-Insulin (INS) antibody (ABIN3020884) anti-Insulin (INS) antibody