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General |
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Antigen | Insulin (INS) Antibodies |
Reactivity | Cow (Bovine), Human, Pig (Porcine) Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This Insulin antibody is un-conjugated Alternatives |
Application |
Blocking Reagent (BR), ELISA, Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Radioimmunoassay (RIA)
Alternatives
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Supplier | Log in to see |
Product Details anti-Insulin AntibodyTarget Details Insulin Application Details Handling Images |
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Specificity | Reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma |
Purification | Protein A purified |
Immunogen |
Porcine insulin. Type of Immunogen: Purified protein |
Clone | IN-05 |
Isotype | IgG1 |
Plasmids, Primers & others | |
Target Details InsulinProduct Details anti-Insulin Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | Insulin (INS Antibody Abstract) |
Background |
Name/Gene ID: INS Family: Hormone Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin |
Gene ID | 3630 |
UniProt | P01308 |
Pathways | NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation |
Application DetailsProduct Details anti-Insulin Antibody Target Details Insulin Handling Images back to top |
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Application Notes |
Approved: Block, ELISA, Func, ICC, IHC, IHC-P, Neut, RIA Usage: Functional Application: The antibody IN-05 blocks binding of insulin to the receptor. |
Comment |
Target Species of Antibody: Pig |
Restrictions | For Research Use only |
HandlingProduct Details anti-Insulin Antibody Target Details Insulin Application Details Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | PBS, 15 mM sodium azide, approx, pH 7.4. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | avoid freeze thaw cycles. |
Storage | 4 °C,-20 °C |
Storage Comment | Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. |