anti-Rat (Rattus) Insulin antibody for Immunohistochemistry (Frozen Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
876
391
262
257
206
120
49
6
6
6
5
4
4
2
2
1
1
1
1
1
1
1
Host
Mouse
708
179
53
16
3
1
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
47
38
37
23
22
22
22
17
17
14
14
14
14
14
14
14
14
10
9
8
8
8
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
507
352
229
205
189
181
147
124
66
64
33
25
15
11
8
6
5
4
4
3
3
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN112214
$ 434.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN255726 IHC (fro) IHC (p) IHC ELISA Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN768892 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7 0
1 ABIN1804388 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN1723784 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7 0
1 ABIN115757 IHC (fro) IF IHC (p) Guinea Pig Log in to see Polyclonal 4
1 ABIN112204 EIA IHC (fro) Mouse IgG1 Log in to see 5E4-3 0
1 ABIN268022 IHC (fro) IHC ELISA Mouse IgG1 kappa Log in to see D6C4 0
1 ABIN1959952 IHC (fro) IHC (p) ELISA Mouse IgG1, kappa Log in to see D6C4 0
1 ABIN599769 IHC (fro) IHC (p) ELISA Rabbit Log in to see Polyclonal 0
1 ABIN114751 IHC (fro) IHC (p) Mouse IgG1 Log in to see K36aC10 2
1 ABIN4326190 ELISA IHC (fro) IHC (p) PerCP Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326197 ELISA IHC (fro) IHC (p) DyLight 650 Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326194 ELISA IHC (fro) IHC (p) Alexa Fluor 700 Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326196 ELISA IHC (fro) IHC (p) Biotin Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326135 ELISA IHC IHC (fro) Biotin Mouse IgG1 kappa Log in to see D6C4 0
1 ABIN4326191 ELISA IHC (fro) IHC (p) Alexa Fluor 405 Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326193 ELISA IHC (fro) IHC (p) Alexa Fluor 647 Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326192 ELISA IHC (fro) IHC (p) Alexa Fluor 488 Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326198 ELISA IHC (fro) IHC (p) FITC Mouse IgG1 Log in to see D3E7 (5B6-6) 0
1 ABIN4326200 ELISA IHC (fro) IHC (p) DyLight 488 Mouse IgG1 Log in to see D3E7 (5B6-6) 0

General

Antigen Insulin (INS) Antibodies
Reactivity Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(876), (391), (262), (257), (206), (120), (49), (6), (6), (6), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(708), (179), (53), (16), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(47), (38), (37), (23), (22), (22), (22), (17), (17), (14), (14), (14), (14), (14), (14), (14), (14), (10), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(507), (352), (229), (205), (189), (181), (147), (124), (66), (64), (33), (25), (15), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN112214) Images
Specificity This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.Aff. Const.:6.3 x 108 M-1
Cross-Reactivity (Details) Also reacts to: Proinsulin
Purification Affinity Chromatography on Protein A
Immunogen Recombinant Human Insulin.
Clone D3E7 (5B6-6)
Isotype IgG1

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN112214) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN112214) Images back to top
Application Notes Immunohistochemistry on Frozen Sections. ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Captureantibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN112214) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN112214)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Qin, Jiao, Chen, Zhou, Liang, Zhong: "Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival." in: Life sciences, Vol. 84, Issue 23-24, pp. 810-6, 2009

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN112214) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin (INS) antibody (ABIN112214) Staining of paraffin embedded human pancreas with mouse anti rat Insulin.