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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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9.122962 | ABIN2470125 | IHC WB | Rabbit | IgG | AA 38-54 | Log in to see | Polyclonal | 0 | ||
9.122962 | ABIN1845968 | FACS IHC ELISA WB | Mouse | IgG1 | Log in to see | 0 | ||||
9.122962 | ABIN4327516 | ELISA FACS IHC WB | Mouse | IgG1 | Log in to see | 2H9 | 0 | |||
9.122962 | ABIN2421751 | IHC ELISA | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN4327517 | DB ELISA IHC IHC (p) IP WB | Mouse | IgG1 kappa | pThr345 | Log in to see | A8A8 | 0 | ||
1 | ABIN1882335 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN4880340 | ELISA FACS IHC WB | Mouse | IgG1 | Log in to see | 2H9 | 0 | |||
1 | ABIN2881541 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN5682779 | ELISA FACS IHC WB | Mouse | IgG1 | Log in to see | 2H9 | 0 | |||
1 | ABIN2887512 | IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN2290774 | IHC WB | Rabbit | IgG | N-Term, AA 38-54 | Log in to see | Polyclonal | 0 | ||
1 | ABIN2968760 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
1 | ABIN4901815 | ELISA FACS IHC WB | Mouse | IgG1 | Log in to see | 2H9 | 0 |
General |
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Antigen | Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies |
Reactivity | Human, Mouse (Murine), Monkey Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This IRAK4 antibody is un-conjugated Alternatives |
Application |
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives
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2 references available |
Supplier | Log in to see |
Product Details anti-IRAK4 AntibodyTarget Details IRAK4 Application Details Handling References for anti-IRAK4 antibody (ABIN969218) Images |
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Purification | Ascites |
Immunogen | Purified recombinant fragment of human IRAK4 expressed in E. Coli. |
Clone | 2H9 |
Isotype | IgG1 |
Target Details IRAK4Product Details anti-IRAK4 Antibody Application Details Handling References for anti-IRAK4 antibody (ABIN969218) Images back to top |
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Antigen | |
Alternative Name | IRAK4 (IRAK4 Antibody Abstract) |
Background | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Molecular Weight | 52 kDa |
Gene ID | 51135 |
HGNC | 51135 |
Pathways | NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades |
Application DetailsProduct Details anti-IRAK4 Antibody Target Details IRAK4 Handling References for anti-IRAK4 antibody (ABIN969218) Images back to top |
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Application Notes | ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400 |
Restrictions | For Research Use only |
HandlingProduct Details anti-IRAK4 Antibody Target Details IRAK4 Application Details References for anti-IRAK4 antibody (ABIN969218) Images back to top |
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Format | Liquid |
Buffer | Ascitic fluid containing 0.03 % sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C,-20 °C |
Storage Comment | 4°C, -20°C for long term storage |
References for anti-IRAK4 antibody (ABIN969218)Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling Images back to top |
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Product cited in: |
Dunne, Carpenter, Brikos, Gray, Strelow, Wesche, Morrice, ONeill: "IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18276-82, 2010 Pathak, De Souza, Salte, Wiker, Asjö: "HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells." in: Scandinavian journal of immunology, Vol. 70, Issue 3, pp. 264-76, 2009 |
ImagesProduct Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling References for anti-IRAK4 antibody (ABIN969218) back to top |
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Supplier Images |
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