anti-Dog (Canine) BAX antibody for Immunohistochemistry

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Epitope
N-Term
87
77
31
22
21
19
15
13
12
12
11
10
9
9
9
7
7
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Pig (Porcine)
555
233
213
128
43
30
28
22
21
11
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
346
243
4
2
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
14
12
11
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
453
230
193
168
143
140
113
47
42
40
32
26
13
5
5
2
2
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2792125
$ 229.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.58659 ABIN2707357 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN202051 IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN386425 IF IHC IHC (p) WB Mouse IgG1, kappa AA 3-16 Log in to see 2D2 0
1 ABIN957154 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 0
1 ABIN2463657 IHC ELISA WB Rabbit Log in to see Polyclonal 0
1 ABIN386428 IF IHC IHC (p) WB Biotin Mouse IgG1, kappa AA 3-16 Log in to see 2D2 0
1 ABIN4283100 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 0
1 ABIN2738495 ELISA FACS IF IHC IHC (p) IP WB Mouse IgG1 Log in to see 2D2 0
1 ABIN2589881 ELISA IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN4283099 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 0
1 ABIN2994423 ELISA IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope N-Term
(87), (77), (31), (22), (21), (19), (15), (13), (12), (12), (11), (10), (9), (9), (9), (7), (7), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Pig (Porcine)
(555), (233), (213), (128), (43), (30), (28), (22), (21), (11), (7), (7), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(346), (243), (4), (2)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (14), (12), (11), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(453), (230), (193), (168), (143), (140), (113), (47), (42), (40), (32), (26), (13), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN2792125) Images
Sequence MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV
Predicted Reactivity Cow: 100%, Dog: 100%, Human: 100%, Pig: 100%
Characteristics This is a rabbit polyclonal antibody against BAX. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human BAX
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN2792125) Images back to top
Antigen
Alternative Name BAX (BAX Antibody Abstract)
Background BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Alias Symbols: BCL2L4
Protein Interaction Partner: CYCS, ZBTB24, UBC, CASP9, CASP8, CASP7, CASP3, BCL2L1, BCL2, CLU, MDM2, MCL1, BAX, BAG3, YWHAB, VCP, CRYAB, CRYAA, BAK1, XIAP, TP53, KCNA3, HSPA4, XRCC6, XRCC5, HDAC6, BAD, PSMC5, PSMC3, PARK7, UHRF2, RNF144B, OYE2, TOMM22, TOMM40, MEPCE, MOAP1, BBC3, PPP
Protein Size: 192
Molecular Weight 21 kDa
Gene ID 581
NCBI Accession NM_138761, NP_620116
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN2792125) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 192 AA

Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN2792125) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BAX antibody (ABIN2792125)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

De Martino, Marfé, Longo, Fiorito, Montagnaro, Iovane, Decaro, Pagnini: "Bid cleavage, cytochrome c release and caspase activation in canine coronavirus-induced apoptosis." in: Veterinary microbiology, Vol. 141, Issue 1-2, pp. 36-45, 2010

Honda, Abe, Hiroki, Honda, Iwanuma, Yanagisawa, Ide: "Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis." in: Journal of muscle research and cell motility, Vol. 28, Issue 4-5, pp. 243-7, 2007

Background publications

Yamaguchi, Chen, Bhalla, Wang: "Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39431-7, 2004

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN2792125) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN2792125) WB Suggested Anti-BAX Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell l...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN2792125) Rabbit Anti-BAX Antibody AV Paraffin Embedded Tissue: Human cardiac cell Cell...
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN2792125) Lanes: 1. Human NT-2 cells (60ug) lysate 2. Mouse WT brain extract (80ug) Primary ...
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN2792125) Immunohistochemistry with NT2, mouse brain; rat brain. tissue
Immunohistochemistry (IHC) image for anti-BCL2-Associated X Protein (BAX) (N-Term) antibody (ABIN2792125) Human kidney