anti-Human BAX antibody for Western Blotting

Recommended BAX Antibody (supplied by: Log in to see )

Antigen
BCL2-Associated X Protein (BAX) Antibodies
  • BAX-ALPHA
  • bax-A
  • xBax
  • xlbax
  • BAX
  • bax
  • fj16e01
  • wu:fc50b10
  • wu:fj16e01
  • BCL2L4
  • BCL2 associated X, apoptosis regulator
  • BCL2-associated X protein L homeolog
  • BCL2-associated X protein
  • bcl2-associated X protein, a
  • BAX
  • bax.L
  • bax
  • baxa
  • Bax
Epitope
AA 19-33, N-Term
92
77
31
22
21
17
15
13
12
12
10
10
10
10
10
7
7
5
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
556
240
217
123
42
31
26
23
21
9
6
5
5
3
3
2
1
1
1
1
Host
Rabbit
351
241
4
Clonality
Polyclonal
Conjugate
This BAX antibody is un-conjugated
19
15
15
13
12
9
8
6
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Western Blotting (WB)
454
233
195
158
144
143
122
45
42
40
34
26
13
5
5
2
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN5518641
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1680813 ABIN725390 FACS IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 60-110 Log in to see Polyclonal 24
3.1680813 ABIN222887 IP WB Rabbit IgG N-Term Log in to see Polyclonal 5
3.1680813 ABIN2787858 WB Rabbit N-Term Log in to see Polyclonal 0
3.1680813 ABIN2787859 WB Rabbit Middle Region Log in to see Polyclonal 0
3.1680813 ABIN388094 FACS IHC (p) WB Rabbit Ig Fraction AA 41-76, BH3 Domain Log in to see Polyclonal 8
3.1680813 ABIN2792125 IHC WB Rabbit N-Term Log in to see Polyclonal 3
3.1680813 ABIN4283102 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
3.1680813 ABIN2707357 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
3.1680813 ABIN2957872 IC IF WB Rabbit C-Term Log in to see Polyclonal 0
3.1680813 ABIN2705572 IC IF IHC ELISA WB Rabbit Center Log in to see Polyclonal 0
3.1680813 ABIN2705573 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
3.1680813 ABIN1532504 IF ELISA WB Rabbit IgG AA 133-182 Log in to see Polyclonal 2
3.1680813 ABIN1534426 IF IHC ELISA WB Rabbit IgG AA 41-90 Log in to see Polyclonal 2
3.1680813 ABIN2707358 IHC WB Rabbit N-Term Log in to see Polyclonal 0
3.1680813 ABIN4283098 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 3
3.1680813 ABIN682843 IF (p) IHC (p) WB Rabbit IgG AA 179-192, pSer184 Log in to see Polyclonal 5
3.1680813 ABIN451743 ELISA FACS ICC IF IHC IHC (fro) IP WB Mouse IgG1 kappa N-Term Log in to see 6A7 3
3.1680813 ABIN4283096 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 2
3.1680813 ABIN5518740 IHC (p) WB Rabbit IgG AA 17-48, N-Term Log in to see Polyclonal 0
3.1680813 ABIN3183487 ELISA IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0

General

Antigen BCL2-Associated X Protein (BAX) Antibodies
Epitope AA 19-33, N-Term
(92), (77), (31), (22), (21), (17), (15), (13), (12), (12), (10), (10), (10), (10), (10), (7), (7), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(556), (240), (217), (123), (42), (31), (26), (23), (21), (9), (6), (5), (5), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(351), (241), (4)
Clonality
Polyclonal
Conjugate This BAX antibody is un-conjugated
(19), (15), (15), (13), (12), (9), (8), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Western Blotting (WB)
(454), (233), (195), (158), (144), (143), (122), (45), (42), (40), (34), (26), (13), (5), (5), (2), (2), (1), (1), (1), (1), (1)
Pubmed 67 references available
Supplier Log in to see

Product Details anti-BAX Antibody

Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN5518641) Images
Purpose Rabbit IgG polyclonal antibody for Apoptosis regulator BAX(BAX) detection. Tested with WB in Human,Mouse,Rat.
Sequence IMKTGALLLQ GFIQD
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Apoptosis regulator BAX(BAX) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: BCL2-associated X protein
Protein Name: Apoptosis regulator BAX
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human Bax(19-33aa IMKTGALLLQGFIQD), different from the related mouse and rat sequences by one amino acid.
Isotype IgG
Plasmids, Primers & others

Target Details BAX

Product Details anti-BAX Antibody Application Details Handling References for anti-BAX antibody (ABIN5518641) Images back to top
Antigen
Alternative Name BAX (BAX Antibody Abstract)
Background Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. Additionally, this protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Synonyms: apoptosis regulator BAX antibody|Apoptosis regulator BAX cytoplasmic isoform beta antibody|Apoptosis regulator BAX membrane isoform alpha antibody|BAX antibody|Bax isoform psi antibody|BAX protein cytoplasmic isoform delta antibody|Bax protein cytoplasmic isoform delta. antibody|Bax protein cytoplasmic isoform gamma antibody|Bax zeta antibody|Bax-protein antibody|BAX_HUMAN antibody|Bcl-2-like protein 4 antibody|BCL2 associated X protein antibody|BCL2 associated X protein omega antibody|BCL2 associated X protein transcript variant delta2 antibody|Bcl2-L-4 antibody, BCL2L4 antibody
UniProt Q07812
Pathways p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-BAX Antibody Target Details BAX Handling References for anti-BAX antibody (ABIN5518641) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only

Handling

Product Details anti-BAX Antibody Target Details BAX Application Details References for anti-BAX antibody (ABIN5518641) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-BAX antibody (ABIN5518641)

Product Details anti-BAX Antibody Target Details BAX Application Details Handling Images back to top
Product cited in:

Xu, Liu, Zhang, Wang, Wang, Yang, Huo, Sun: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, 2015

Ding, Wang, Zhao, Sun, Zhai: "Protective Effects of Baicalin on A?????-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat." in: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 623-32, 2015

Yang, Li, Liu, Shi, Zhang: "Inhibitory effect of tetramethylpyrazine preconditioning on overload training-induced myocardial apoptosis in rats." in: Chinese journal of integrative medicine, Vol. 21, Issue 6, pp. 423-30, 2015

Zhou, Lu, Liu, Guo, Liu, Zhou, Yang, Mi, Xu: "Platycodin D induces tumor growth arrest by activating FOXO3a expression in prostate cancer in vitro and in vivo." in: Current cancer drug targets, Vol. 14, Issue 9, pp. 860-71, 2015

Li, Wang, Wang: "Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina." in: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Vol. 31, Issue 4, pp. 352-9, 2015

Peng, Chen, Chen, Fang, Cui, Zuo, Deng, Chen, Geng, Lai: "Aflatoxin B1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens." in: Environmental toxicology, 2015

Tang, Zhang, Qi, Chen, Li, Liu, He, Li, Zu: "Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line." in: Experimental and therapeutic medicine, Vol. 9, Issue 5, pp. 1851-1856, 2015

Zhao, Chen, Li, Tang, Liu, Yang: "Doxorubicin and curcumin co-delivery by lipid nanoparticles for enhanced treatment of diethylnitrosamine-induced hepatocellular carcinoma in mice." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V, Vol. 93, pp. 27-36, 2015

Yin, Li, Li, Yu, Cai, Zhang, Wang, Zhang, Zhou, Cheng, Gao: "Critical role of prohibitin in endothelial cell apoptosis caused by glycated low-density lipoproteins and protective effects of grape seed procyanidin B2." in: Journal of cardiovascular pharmacology, Vol. 65, Issue 1, pp. 13-21, 2015

Liu, Zheng, Wang, Han, Yuan, Zhao: "Transplantation of olfactory ensheathing cells attenuates acute carbon monoxide poisoning-induced brain damages in rats." in: Neurochemical research, Vol. 40, Issue 1, pp. 70-80, 2015

Wang, Zhang, Chai, Liu, Berk: "The effects of escitalopram on myocardial apoptosis and the expression of Bax and Bcl-2 during myocardial ischemia/reperfusion in a model of rats with depression." in: BMC psychiatry, Vol. 14, pp. 349, 2015

Wu, Dong, Li: "Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload." in: International journal of molecular medicine, Vol. 35, Issue 4, pp. 893-900, 2015

Sun, Zhang, Guan, Zhou, Sun: "Alpha-lipoic acid attenuates trinitrobenzene sulfonic acid-induced ulcerative colitis in mice." in: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 358-67, 2015

Han, Yu, Song, Luo, Wu: "Agmatine protects Müller cells from high-concentration glucose-induced cell damage via N-methyl-D-aspartic acid receptor inhibition." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 1098-106, 2015

Du, Ding, Zou, Li, Tian, She, Wang, Wang, Lv, Chang: "Morphology and Molecular Mechanisms of Hepatic Injury in Rats under Simulated Weightlessness and the Protective Effects of Resistance Training." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127047, 2015

Yan, Wu, Li, Meng, Dai, Zheng, Fu: "Cyanidin-3-O-glucoside Induces Apoptosis and Inhibits Migration of Tumor Necrosis Factor-?-Treated Rat Aortic Smooth Muscle Cells." in: Cardiovascular toxicology, 2015

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." in: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, 2014

Yan, Liang, Zhang, Liu, Bu: "Apoptotic induction of lung adenocarcinoma A549 cells infected by recombinant RVG Newcastle disease virus (rL-RVG) in vitro." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 317-26, 2014

Wei, Tian, Yan, Shao, Xie: "Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells." in: Cellular and molecular neurobiology, Vol. 34, Issue 8, pp. 1165-73, 2014

Mao, Song, Li, Lv, Zhao, Li, Feng, Chen: "8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury." in: Neural regeneration research, Vol. 8, Issue 2, pp. 133-42, 2014

Images

Product Details anti-BAX Antibody Target Details BAX Application Details Handling References for anti-BAX antibody (ABIN5518641) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2-Associated X Protein (BAX) (AA 19-33), (N-Term) antibody (ABIN5518641) Western blot analysis of Bax using anti- Bax antibody . Electrophoresis was performe...
Flow Cytometry (FACS) image for anti-BCL2-Associated X Protein (BAX) (AA 19-33), (N-Term) antibody (ABIN5518641) Flow Cytometry analysis of A431 cells using anti-BAX antibody . Overlay histogram sho...